| Primary information |
|---|
| OV_ID | OV_5343 |
| Virus Name | Newcastle disease virus |
| Strain | LaSota |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human glioblastoma multiforme |
| Cell line | T98G |
| Concentration of cell line | 5 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 0.001 MOI |
| In-vitro result | 29% cells remain viable after 72 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus induce apoptosis |
| Immunogenic effect | Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma |
| Clinical trial | NA |
| PMID | 28293547 |