| Primary information |
|---|
| OV_ID | OV_5336 |
| Virus Name | Newcastle disease virus |
| Strain | NDV/Anh-TRAIL |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | Virus insertion for TRAIL gene |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | China Xiehe Medical University |
| Origin of cell line | Human hepatocellular carcinoma cell line |
| Cell line | HepG2 |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 1 MOI |
| In-vitro result | 29.6% cells remain viable |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus induced apoptosis as measured by TUNEL assay |
| Immunogenic effect | Caspase 3 pathway are activated |
| Clinical trial | NA |
| PMID | 28246027 |