Detailed description page of Selected OV_ID


OV_4945 details
Primary information
OV_IDOV_4945
Virus Name Newcastle disease virus
StrainNDV/Anh
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineHarbin phamaceutical group bioengineering
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismNude mice xenograft for H22 cell line (10⁵ cells)
In-vivo virus concentration1× 10⁷ pfu every other day for four times
In-vivo toxicityNA
In-vivo resultAverage volume in control mice was 3401.25 cubic mm and decreased to 1489.97 cubuc mm in treated mice
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectActivate T cells
Clinical trialNA
PMID27174862