Primary information |
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OV_ID | OV_4392 |
Virus Name | Newcastle disease virus |
Strain | MTH-68/H |
Virus type | RNA |
Virus family | Paramyxoviridae |
Modification in virus genome | None |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human primary melanoma cell line |
Cell line | A375 |
Concentration of cell line | 250 |
In-vitro toxicity | NA |
Assay | Luciferase based ATP assay |
In-vitro virus concentration | 4.43 MOI |
In-vitro result | 80% cancer cell death |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | ER stress and apoptotic pathway |
Immunogenic effect | IFN production increased |
Clinical trial | NA |
PMID | 26408702 |