Detailed description page of Selected OV_ID


OV_5334 details
Primary information
OV_IDOV_5334
Virus Name Newcastle disease virus
StrainNDV/Anh-TRAIL
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeVirus insertion for TRAIL gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineChina Xiehe Medical University
Origin of cell lineHuman hepatocellular carcinoma cell line
Cell lineHepG2
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.01 MOI
In-vitro result56.7% cells remain viable
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induced apoptosis as measured by TUNEL assay
Immunogenic effectCaspase 3 pathway are activated
Clinical trialNA
PMID28246027