The Total number of records shown on this page is 92. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3195	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human edwig sarcoma cell line	RD-ES	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	55% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3196	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human edwig sarcoma cell line	RD-ES	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3197	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human edwig sarcoma cell line	RD-ES	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3198	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human edwig sarcoma cell line	RD-ES	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3199	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human edwig sarcoma cell line	RD-ES	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3200	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human edwig sarcoma cell line	RD-ES	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3225	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	70% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3226	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3227	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3228	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3229	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3230	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3255	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human canine osteosarcoma	D17	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	77% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3256	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human canine osteosarcoma	D17	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	60% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3257	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human canine osteosarcoma	D17	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	52% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3258	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human canine osteosarcoma	D17	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	48% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3259	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human canine osteosarcoma	D17	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3260	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human canine osteosarcoma	D17	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3285	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human synovial sarcoma cell line	SW982	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3286	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human synovial sarcoma cell line	SW982	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3287	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human synovial sarcoma cell line	SW982	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3288	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human synovial sarcoma cell line	SW982	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3289	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human synovial sarcoma cell line	SW982	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	77% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3290	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human synovial sarcoma cell line	SW982	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	75% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3723	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	NA	NA	Absorbance measurements	0.1 MOI	15% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3724	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3M-Luc	NA	NA	Absorbance measurements	0.1 MOI	50% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3725	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	NA	NA	Absorbance measurements	0.1 MOI	1% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3726	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	NA	NA	Absorbance measurements	0.1 MOI	70% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3727	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	NA	NA	Absorbance measurements	0.1 MOI	70% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3728	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	LAPC4	NA	NA	Absorbance measurements	0.1 MOI	30% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3729	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	TRAMP-C1	NA	NA	Absorbance measurements	0.1 MOI	5% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3730	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	NA	NA	Absorbance measurements	10 MOI	15% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3731	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3M-Luc	NA	NA	Absorbance measurements	10 MOI	18% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3732	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	NA	NA	Absorbance measurements	10 MOI	3% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3733	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	NA	NA	Absorbance measurements	10 MOI	15% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3734	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	NA	NA	Absorbance measurements	10 MOI	30% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3735	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	LAPC4	NA	NA	Absorbance measurements	10 MOI	10% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3736	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	TRAMP-C1	NA	NA	Absorbance measurements	10 MOI	5% cell viable	No	No	NA	No response	Virus induce apoptosis in cancer cell	NA	NA	NA	29696636
OV_3737	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for Du145 (2.0E+6)	1.0E+7 pfu	NA	Complete regression in tumor after day 80	Intratumoral	NA	NA	NA	29696636
OV_3738	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	22RV1	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)	1.0E+7 pfu	NA	Regression in tumor volume to 0.4 cm after day 80	Intratumoral	NA	NA	NA	29696636
OV_3739	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	22RV1	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)	1.0E+7 pfu	NA	Complete regression in tumor after day 80	Intravenous	NA	NA	NA	29696636
OV_3740	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for VCap (2.0E+6)	1.0E+7 pfu	NA	Regression in tumor volume to 0.3 cm after day 80	Intratumoral	NA	NA	NA	29696636
OV_4395	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and c-Myc gene	No	VSV-HIF2alpha+ VSV-sox10+ VSV-cMYC	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	60% mice survived on day 30, 20% mice survived on day 45 and last mice survived on day 60	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4396	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and GFP gene	No	VSV-HIF2alpha+ VSV-sox10+ VSV-GFP	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	All mice survived upto day 30 fter that all was dead	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4397	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing N-Ras, cytC and TYRP-1 gene	No	VSV-N-Ras+VSV-cytC+ VSV-TYRP-1	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	All mice survived upto day 10 fter that all was dead	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4398	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and c-Myc gene	No	VSV-HIF2alpha, VSV-Sox10+ VSV-cMyc+antiPD1	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	Mice survived upto day 45	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4399	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and c-Myc gene	No	VSV-HIF2alpha, VSV-Sox10+ VSV-cMyc+IgG	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	Mice survived upto day 35	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4400	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	virus expressing GFP	No	VSV-GFp+anti-GFP	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	Mice survived upto day 12	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4422	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	48% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4423	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human brain cancer cell line	U343	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	25% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4424	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human brain cancer cell line	U-87 MG	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	52% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4425	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human liver cancer cell line	Hep3B	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	70% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4426	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human cervical cancer cell line	C33A	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	50% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4427	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human cervical cancer cell line	HeLa	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	60% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4428	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human breast cancer cell line	MCF-7	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	48% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4429	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human breast cancer cell line	MDA-MB-435	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	98% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4430	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	20% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4431	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human brain cancer cell line	U343	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	20% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4432	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human brain cancer cell line	U-87 MG	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	30% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4433	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human liver cancer cell line	Hep3B	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	30% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4434	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human cervical cancer cell line	C33A	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	48% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4435	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human cervical cancer cell line	HeLa	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	20% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4436	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human breast cancer cell line	MCF-7	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	1% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4437	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human breast cancer cell line	MDA-MB-435	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	2% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4438	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	male athymic nude mice xenograft for A549 (1.0E+7)	5.0E+9 pfu	NA	Tumor volume become below 600 cubic millimeter after 71 days compared to control 1000	Intratumoral	NA	NA	NA	26430798
OV_4439	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	male athymic nude mice xenograft for A549 (1.0E+7)	5.0E+9 pfu	NA	Tumor volume become below 100 cubic millimeter after 71 days compared to control 1000	Intratumoral	NA	NA	NA	26430798
OV_4440	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	male athymic nude mice xenograft for MCF7 (1.0E+7)	5.0E+10 pfu	NA	Tumor volume become below 1500 cubic millimeter after 49 days compared to control 4000	Intratumoral	NA	NA	NA	26430798
OV_4441	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	male athymic nude mice xenograft for MCF7 (1.0E+7)	5.0E+10 pfu	NA	Tumor volume become below 600 cubic millimeter after 49 days compared to control 4000	Intratumoral	NA	NA	NA	26430798
OV_5160	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	40% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5161	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	60% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5162	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5163	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	A2780	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5164	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	SKOV6	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	70% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5165	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	SKOV6	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	70% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5166	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	SKOV6	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	30% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5167	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	SKOV6	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	20% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5168	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	SKOV6	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	10% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5169	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	SKOV6	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	15% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5170	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	HOC7	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	90% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5171	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	HOC7	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	90% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5172	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	HOC7	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	60% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5173	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	HOC7	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	50% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5174	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	University of vienna	Human ovarian cancer cell line	HOC7	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	40% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5175	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	University of vienna	Human ovarian cancer cell line	HOC7	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	40% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5176	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5177	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell viable after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5178	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	100% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5179	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	20% cell viable after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5180	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	80% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5181	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	Yes	No	No	ATCC	Human ovarian cancer cell line	OVCAR3	1.0E+5 cells per well	NA	WST-1 assay	1 MOI	10% cell viable after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27738655
OV_5182	Vesicular stomatitis virus	VSV-deltaGP	RNA	Rhabdoviridae	Virus lacking envelope protein G	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for A2780 (5.0E+6 cells)	2.0E+5 pfu	NA	Reduction in tumor volume to 0.1 cubic cm compared to control 0.7 cubic cm	Intratumoral	NA	NA	NA	27738655
OV_5183	Vesicular stomatitis virus	VSV-MqdeltaG	RNA	Rhabdoviridae	Attenuated strain with 4 mutation in M protein and lacking G protein	No	Virus in combination with Ruxolinitib 1 micromolar per litre	No	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice xenograft for A2780 (5.0E+6 cells)	2.0E+5 pfu	NA	Reduction in tumor volume to 0.1 cubic cm compared to control 0.7 cubic cm and increase in survival time to beyond 100 days compared to drug and alone	Intratumoral	NA	NA	NA	27738655