Detailed description page of Selected OV_ID


OV_5182 details
Primary information
OV_IDOV_5182
Virus Name Vesicular stomatitis virus
StrainVSV-deltaGP
Virus typeRNA
Virus familyRhabdoviridae
Modification in virus genomeVirus lacking envelope protein G
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismSCID mice xenograft for A2780 (5 × 10⁶cells)
In-vivo virus concentration2 × 10⁵ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to 0.1 cubic cm compared to control 0.7 cubic cm
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27738655