Detailed description page of Selected OV_ID


OV_4439 details
Primary information
OV_IDOV_4439
Virus Name Vesicular stomatitis virus
StrainRdB-1L-VSVG
Virus typeRNA
Virus familyRhabdoviridae
Modification in virus genomeVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismmale athymic nude mice xenograft for A549 (1 × 10⁷)
In-vivo virus concentration5 × 10⁹ pfu
In-vivo toxicityNA
In-vivo resultTumor volume become below 100 cubic millimeter after 71 days compared to control 1000
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26430798