Detailed description page of Selected OV_ID


OV_4440 details
Primary information
OV_IDOV_4440
Virus Name Vesicular stomatitis virus
StrainRdB
Virus typeRNA
Virus familyRhabdoviridae
Modification in virus genomeVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismmale athymic nude mice xenograft for MCF7 (1 × 10⁷)
In-vivo virus concentration5 × 10¹⁰ pfu
In-vivo toxicityNA
In-vivo resultTumor volume become below 1500 cubic millimeter after 49 days compared to control 4000
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26430798