Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_897Herpes simplex virusMutantDNAHerpesviridaeDeletion mutant for Gamma 34.5YesNoNoATCCNANANANANANANAHsd athymic nude mice xenograft for Hep 3B cancer cell line1.0E+7 pfu NA Complete reduction in tumor nodes after 4 weeksintraperitonialNANANA12788648
OV_916Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCNANANANANANANABALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line2.0E+7 pfu NA 30% reduction in tumor volumeTail vein injection of virusNANANA15129429
OV_917Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCNANANANANANANABALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line2.0E+7 pfu NA 50% reduction in tumor volumeTail vein injection of virusNANANA15129429
OV_918Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCNANANANANANANABALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line2.0E+7 pfu NA 60% reduction in tumor volumeTail vein injection of virusNANANA15129429
OV_919Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCNANANANANANANABALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model2.0E+7 pfu NA Lung metastasis were not detected after 40 days when stained with bouins fixativeTail vein injection of virusNANANA15129429
OV_920Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCNANANANANANANABALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model2.0E+7 pfu NA Lung metastasis were not detected after 40 days when stained with bouins fixativeTail vein injection of virusNANANA15129429
OV_921Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCNANANANANANANABALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model2.0E+7 pfu NA Lung metastasis were not detected after 40 days when stained with bouins fixativeTail vein injection of virusNANANA15129429
OV_1915Vaccinia virusGLV-1h68DNAPoxviridaeNoneYesNoNoATCCMalignan small cell canine carcinoma cell lineMTH52cNANANANANAHsd athymic nude mice xenograft for MTH52c cell line5.0E+6 pfuNA Significant decrease in tumor volume after 42 daysNANAVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alphaNA20631910
OV_2063Vaccinia virusGLV-1h68DNAPoxviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell linePLCNANANANANAAthymic hsd nude mice xenograft for PLC cell line5.0E+6 pfuReduction in tumor volume below 2000mm compared to control after 45 days No responseNAInduction of apoptosis in cancer cell lineIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2NA21779374
OV_2064Vaccinia virusGLV-1h68DNAPoxviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineHuh-7NANANANANAAthymic hsd nude mice xenograft for PLC cell line5.0E+6 pfuReduction in tumor volume below 3000mm compared to control after 35 days NAInduction of apoptosis in cancer cell lineIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2NA21779374
OV_2526Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1NANANANANAHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells)2.0E+6 pfuNA Decrease in tumor volume below 2 after 34 daysIntratumoralNANANA22258815
OV_2527Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1NANANANANAHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells)2.0E+6 pfuNA Decrease in tumor volume below 2 after 34 daysIntravenousNANANA22258815
OV_2843Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-116NANANANANAHsd:athymic nude mice xenograft for HCT-116 (5.0E+6 cells)5.0E+6 pfuNA Significant reduction in tumor volume after 42 daysIntratumoralNANANA23531320
OV_3002PoxvirusCF33-hNISDNAPoxviridaeInsertion of gene encoding human hNISYesNoNoATCCHuman colorectal cancer cell lineHCT-116NANANANANAHsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells)1.0E+5 pfuNA Complete regression in tumor volume after 55 daysIntratumoralImmunogenicity followed by virus induced cell deathNANA31061881
OV_3003PoxvirusCF33-hNISDNAPoxviridaeInsertion of gene encoding human hNISYesNoNoATCCHuman colorectal cancer cell lineHT-29NANANANANAHsd:athymic nude mice xenograft for HT-29 (5.0E+6 cells)1.0E+5 pfuNA Tumor volume reached 1500mm after day 50IntratumoralImmunogenicity followed by virus induced cell deathNANA31061881
OV_3004PoxvirusCF33-hNISDNAPoxviridaeInsertion of gene encoding human hNISNoVirus in combination with I-131NoATCCHuman colorectal cancer cell lineHCT-116NANANANANAHsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells)1.0E+4 pfuNA Reduction in tumor volume below 100mm after 55 daysIntravenousImmunogenicity followed by virus induced cell deathNANA31061881
OV_3005PoxvirusCF33-hNISDNAPoxviridaeInsertion of gene encoding human hNISNoVirus in combination with I-131NoATCCHuman colorectal cancer cell lineHT-29NANANANANAHsd:athymic nude mice xenograft for HT-29 (3.0E+9 cells)1.0E+4 pfuNA Reduction in tumor volume below 300mm after 45 daysIntravenousImmunogenicity followed by virus induced cell deathNANA31061881
OV_4108Vaccinia virusVVstrain LIVP 6.1.1DNAPoxviridaeMutant for J2R geneYesNoNoUniversity of colorado, USANANANANANANANAHsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume reduced to 1000 mm compared to control 2500mm after 42 daysIntravenousNANANA26205404
OV_4109Vaccinia virusVVstrain GLV-5b451DNAPoxviridaeDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locusYesNoNoUniversity of colorado, USANANANANANANANAHsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume reduced to 200 mm compared to control 2500mm after 49 daysIntravenousNANANA26205404
OV_5682Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 261.8mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5683Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 248.4mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5684Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 216.8mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5685Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 208.8mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5686Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 157.2mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5687Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 280.3mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5688Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 301.9mm compared to control 240.8 mm after 33 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5689Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 273.5mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5690Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 243.8mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5691Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 286mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5692Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 267.1mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5693Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 155.6mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5694Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 310.9mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5695Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 416.9mm compared to control 263.6 mm after 36 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5696Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 536.1mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5697Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 5550.4mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5698Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 463.4mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5699Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 543.3mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5700Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 320.1mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5701Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 679mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5702Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 660mm compared to control 579.1 mm after 43 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5703Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 701.4mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5704Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 761.3mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5705Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 706.6mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5706Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 721.3mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5707Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 476.3mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5708Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 864.1mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5709Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 828.6mm compared to control 636.4 mm after 50 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5710Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 978.4mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5711Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 852mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5712Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 985.5mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5713Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 936.1mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5714Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 695mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5715Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1179.9mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5716Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 897.4mm compared to control 671.6 mm after 57 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5717Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1485mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5718Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1053mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5719Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 852mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5720Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 606mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5721Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 751mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5722Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 166.7mm compared to control 2715 mm after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5723Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Complete regression in tumor volume after 92 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5724Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 1536.9mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5725Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 962.2mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5726Vaccinia virusGLV-1h70DNAPoxviridaeInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 579.2mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5727Vaccinia virusGLV-1h71DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 546.9mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5728Vaccinia virusGLV-1h72DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vectorYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 720.1mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5729Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume become 117.8mm compared to control 2918.3 mm after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5730Vaccinia virusGLV-1h74DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusAYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Complete regression in tumor volume after 97 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5731Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 412.9mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5732Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 350.2mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5733Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 341.1mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5734Vaccinia virusGLV-1h82DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 353.4mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5735Vaccinia virusGLV-1h83DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 392.25mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5736Vaccinia virusGLV-1h84DNAPoxviridaeInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 305.6mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5737Vaccinia virusGLV-1h85DNAPoxviridaeInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 350.65mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5738Vaccinia virusGLV-1h86DNAPoxviridaeInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 419.55mm after 39 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5739Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 750.4mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5740Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 722.3mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5741Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 819.8mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5742Vaccinia virusGLV-1h82DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1081.2mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5743Vaccinia virusGLV-1h83DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1222.25mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5744Vaccinia virusGLV-1h84DNAPoxviridaeInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 604.3mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5745Vaccinia virusGLV-1h85DNAPoxviridaeInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 914mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5746Vaccinia virusGLV-1h86DNAPoxviridaeInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 962.1mm after 47 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5747Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1424.4mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5748Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1390.35mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5749Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 983.2mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5750Vaccinia virusGLV-1h82DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1319.2mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5751Vaccinia virusGLV-1h83DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1686.05mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5752Vaccinia virusGLV-1h84DNAPoxviridaeInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 982mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5753Vaccinia virusGLV-1h85DNAPoxviridaeInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 947.2mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5754Vaccinia virusGLV-1h86DNAPoxviridaeInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1397.55mm after 62 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5755Vaccinia virusGLV-1h22DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1907.5mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5756Vaccinia virusGLV-1h68DNAPoxviridaeInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectivelyYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1528.95mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5757Vaccinia virusGLV-1h73DNAPoxviridaeInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locusYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 517.3mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5758Vaccinia virusGLV-1h82DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1211.8mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5759Vaccinia virusGLV-1h83DNAPoxviridaeInsertion of Ruc-GFP gene at place of HA gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 1856.35mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5760Vaccinia virusGLV-1h84DNAPoxviridaeInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoterYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 614.25mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5761Vaccinia virusGLV-1h85DNAPoxviridaeInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 255.25mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968
OV_5762Vaccinia virusGLV-1h86DNAPoxviridaeInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA geneYesNoNoNANANANANANANANAHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)5.0E+6 pfuNA Tumor volume becomes 689.6mm after 75 daysIntravenouslyInduction of apoptosisNANAUS8052968