| Primary information |
|---|
| OV_ID | OV_2526 |
| Virus Name | Vaccinia virus |
| Strain | GLV-1h151 |
| Virus type | DNA |
| Virus family | Poxviridae |
| Modification in virus genome | Deteltion of TK gene and addition of GFP gene |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human pancreatic cancer cell line |
| Cell line | PANC-1 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | Hsd:athymic nude mice xenografted for PANC-1 cell line(2 × 10ⶠcells) |
| In-vivo virus concentration | 2 × 10ⶠpfu |
| In-vivo toxicity | NA |
| In-vivo result | Decrease in tumor volume below 2 after 34 days |
| Mode of delivery | Intratumoral |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 22258815 |