Detailed description page of Selected OV_ID


OV_918 details
Primary information
OV_IDOV_918
Virus Name Herpes simplex virus
StrainSynco-2D
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDouble fusogenic expressing EGFP and GALV.fus protein
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line
In-vivo virus concentration2 × 10⁷ pfu
In-vivo toxicityNA
In-vivo result60% reduction in tumor volume
Mode of deliveryTail vein injection of virus
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID15129429