Detailed description page of Selected OV_ID


OV_897 details
Primary information
OV_IDOV_897
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant for Gamma 34.5
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismHsd athymic nude mice xenograft for Hep 3B cancer cell line
In-vivo virus concentration1 × 10⁷ pfu
In-vivo toxicityNA
In-vivo resultComplete reduction in tumor nodes after 4 weeks
Mode of deliveryintraperitonial
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID12788648