Detailed description page of Selected OV_ID


OV_4108 details
Primary information
OV_IDOV_4108
Virus Name Vaccinia virus
StrainVVstrain LIVP 6.1.1
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeMutant for J2R gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineUniversity of colorado, USA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismHsd athymic nude mice xenograft for STSA-1 cell line (1 × 10⁶)
In-vivo virus concentration1 × 10⁷ pfu
In-vivo toxicityNA
In-vivo resultTumor volume reduced to 1000 mm compared to control 2500mm after 42 days
Mode of deliveryIntravenous
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26205404