Browse By Model Organism Result Page of OvirusTdb
The total number of records retrieved from this search are 100. Click on ID to see further detail.
IDOV_897 | Virus nameHerpes simplex virus | Virus strainMutant | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDeletion mutant for Gamma 34.5 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for Hep 3B cancer cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultComplete reduction in tumor nodes after 4 weeks | Mode of deliveryintraperitonial | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID12788648 |
IDOV_916 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo result30% reduction in tumor volume | Mode of deliveryTail vein injection of virus | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_917 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo result50% reduction in tumor volume | Mode of deliveryTail vein injection of virus | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_918 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo result60% reduction in tumor volume | Mode of deliveryTail vein injection of virus | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_919 | Virus nameHerpes simplex virus | Virus strainBaco-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNon- fusogenic ligated with EGFP protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultLung metastasis were not detected after 40 days when stained with bouins fixative | Mode of deliveryTail vein injection of virus | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_920 | Virus nameHerpes simplex virus | Virus strainSynco-2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationFusogenic membrane ligated with GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultLung metastasis were not detected after 40 days when stained with bouins fixative | Mode of deliveryTail vein injection of virus | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_921 | Virus nameHerpes simplex virus | Virus strainSynco-2D | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationDouble fusogenic expressing EGFP and GALV.fus protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultLung metastasis were not detected after 40 days when stained with bouins fixative | Mode of deliveryTail vein injection of virus | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID15129429 |
IDOV_1915 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for MTH52c cell line | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultSignificant decrease in tumor volume after 42 days | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_2063 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismAthymic hsd nude mice xenograft for PLC cell line | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityReduction in tumor volume below 2000mm compared to control after 45 days | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2064 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismAthymic hsd nude mice xenograft for PLC cell line | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityReduction in tumor volume below 3000mm compared to control after 35 days | In-vivo result | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2526 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultDecrease in tumor volume below 2 after 34 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2527 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenografted for PANC-1 cell line(2.0E+6 cells) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultDecrease in tumor volume below 2 after 34 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2843 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenograft for HCT-116 (5.0E+6 cells) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume after 42 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23531320 |
IDOV_3002 | Virus namePoxvirus | Virus strainCF33-hNIS | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of gene encoding human hNIS | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells) | In-vivo virus concentration1.0E+5 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 55 days | Mode of deliveryIntratumoral | Pathway inducedImmunogenicity followed by virus induced cell death | Immunogenic effectNA | Clinical trialNA | PMID31061881 |
IDOV_3003 | Virus namePoxvirus | Virus strainCF33-hNIS | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of gene encoding human hNIS | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenograft for HT-29 (5.0E+6 cells) | In-vivo virus concentration1.0E+5 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reached 1500mm after day 50 | Mode of deliveryIntratumoral | Pathway inducedImmunogenicity followed by virus induced cell death | Immunogenic effectNA | Clinical trialNA | PMID31061881 |
IDOV_3004 | Virus namePoxvirus | Virus strainCF33-hNIS | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of gene encoding human hNIS | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with I-131 | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-116 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenograft for HCT-116 (2.0E+6 cells) | In-vivo virus concentration1.0E+4 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume below 100mm after 55 days | Mode of deliveryIntravenous | Pathway inducedImmunogenicity followed by virus induced cell death | Immunogenic effectNA | Clinical trialNA | PMID31061881 |
IDOV_3005 | Virus namePoxvirus | Virus strainCF33-hNIS | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of gene encoding human hNIS | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with I-131 | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHT-29 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd:athymic nude mice xenograft for HT-29 (3.0E+9 cells) | In-vivo virus concentration1.0E+4 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume below 300mm after 45 days | Mode of deliveryIntravenous | Pathway inducedImmunogenicity followed by virus induced cell death | Immunogenic effectNA | Clinical trialNA | PMID31061881 |
IDOV_4108 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1000 mm compared to control 2500mm after 42 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4109 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 200 mm compared to control 2500mm after 49 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_5682 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 261.8mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5683 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 248.4mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5684 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 216.8mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5685 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 208.8mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5686 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 157.2mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5687 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 280.3mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5688 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 301.9mm compared to control 240.8 mm after 33 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5689 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 273.5mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5690 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 243.8mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5691 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 286mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5692 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 267.1mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5693 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 155.6mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5694 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 310.9mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5695 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 416.9mm compared to control 263.6 mm after 36 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5696 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 536.1mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5697 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 5550.4mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5698 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 463.4mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5699 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 543.3mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5700 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 320.1mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5701 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 679mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5702 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 660mm compared to control 579.1 mm after 43 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5703 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 701.4mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5704 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 761.3mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5705 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 706.6mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5706 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 721.3mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5707 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 476.3mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5708 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 864.1mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5709 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 828.6mm compared to control 636.4 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5710 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 978.4mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5711 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 852mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5712 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 985.5mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5713 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 936.1mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5714 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 695mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5715 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1179.9mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5716 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 897.4mm compared to control 671.6 mm after 57 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5717 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1485mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5718 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1053mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5719 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 852mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5720 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 606mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5721 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 751mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5722 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 166.7mm compared to control 2715 mm after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5723 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 92 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5724 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 1536.9mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5725 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 962.2mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5726 | Virus nameVaccinia virus | Virus strainGLV-1h70 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, LacZ gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 579.2mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5727 | Virus nameVaccinia virus | Virus strainGLV-1h71 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 546.9mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5728 | Virus nameVaccinia virus | Virus strainGLV-1h72 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA and LacZ at F14.5L gene locus and TK and HA gene locus respectively using P11k vector | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 720.1mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5729 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 117.8mm compared to control 2918.3 mm after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5730 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultComplete regression in tumor volume after 97 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5731 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 412.9mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5732 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 350.2mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5733 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 341.1mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5734 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 353.4mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5735 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 392.25mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5736 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 305.6mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5737 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 350.65mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5738 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 419.55mm after 39 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5739 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 750.4mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5740 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 722.3mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5741 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 819.8mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5742 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1081.2mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5743 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1222.25mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5744 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 604.3mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5745 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 914mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5746 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 962.1mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5747 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1424.4mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5748 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1390.35mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5749 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 983.2mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5750 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1319.2mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5751 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1686.05mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5752 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 982mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5753 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 947.2mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5754 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1397.55mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5755 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1907.5mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5756 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1528.95mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5757 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 517.3mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5758 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1211.8mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5759 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1856.35mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5760 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 614.25mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5761 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 255.25mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5762 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 689.6mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |