MHCBN: A comprehensive database of MHC binding and Non-binding peptides

MHCBN consists of ~25860 MHC binding and non-binding peptides and ~1052.5 peptides interacting with TAP. The database is cross-linked to NCBI, Swiss-Prot, PDB, OMIM and GenBank.

Structures of MHC proteins and MHC-peptide complexes reported in Protein Databank (PDB).

Human

MHC Class I

MHC Class II

Mouse

MHC Class I

MHC Class II

Others

Human (MHC Class I) TOP

MHC Allele	PDB Code	Structure Type	PDB Title/Header
HLA-A*0201	1AO7	MHC+PEPTIDE+TCR	Complex Between Human T-Cell Receptor, Viral Peptide (Tax), And Hla-A 0201
	1B0R	MHC+Peptide	Crystal Structure Of Hla-A0201 Complexed With A Peptide With The Carboxyl-Terminal Group Substituted By A Methyl Group
	1DUZ	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) In Complex With A Nonameric Peptide From Htlv-1 Tax Protein
	1HHG	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) Complex With A Nonameric Peptide From Hiv-1 Gp120 Envelope Protein (Residues 195-207)
	1HHH	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) Complex With A Decameric Peptide From Hepatitis B Nucleocapsid Protein (Residues 18-27)
	1HHI	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) Complex With A Nonameric Peptide From Influenza A Matrix Protein M1 (Residues 58-66)
	1HHJ	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) Complex With A Nonameric Peptide From Hiv-1 Reverse Transcriptase (Residues 309-317)
	1QSE	MHC+PEPTIDE+TCR	Structure Of Human A6-Tcr Bound To Hla-A2 Complexed With Altered Htlv-1 Tax Peptide V7r
	1QSF	MHC+PEPTIDE+TCR	Structure Of A6-Tcr Bound To Hla-A2 Complexed With Altered Htlv-1 Tax Peptide Y8a
	2CLR	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) Complexed With A Decameric Peptide From Calreticulin
	1BD2	MHC+PEPTIDE+TCR	Complex Between Human T-Cell Receptor B7, Viral Peptide (Tax) And Mhc Class I Molecule Hla-A 0201
	1HHK	MHC+Peptide	Human Class I Histocompatibility Antigen (Hla-A 0201) Complex With A Nonameric Peptide From Htlv-1 Tax Protein (Residues 11-19)
HLA-A2*0201	1JF1	MHC+Peptide	Crystal Structure Of Hla-A2*0201 In Complex With A Decameric Altered Peptide Ligand From The Mart-1/Melan-A
HLA-A2*0201	1JHT	MHC+Peptide	Crystal Structure Of Hla-A2*0201 In Complex With A Nonameric Altered Peptide Ligand(Algigiltv) From The Mart- 1/Melan-A.
HLA-A2	1AKJ	MHC+PEPTIDE+TCR	Complex Of The Human Mhc Class I Glycoprotein Hla-A2 And The T Cell Coreceptor Cd8
HLA-A2tax	1IM3	MHC+PEPTIDE+TCR	Crystal Structure Of The Human Cytomegalovirus Protein Us2 Bound To The Mhc Class I Molecule Hla-A2tax
HLA-A2.1	1B0G	MHC+Peptide	Crystal Structure Of Human Class I Mhc (Hla-A2.1) Complexed With Beta 2-Microglobulin And Human Peptide P1049
	1I1F	MHC+Peptide	Crystal Structure Of Human Class I Mhc (Hla-A2.1) Complexed With Beta 2- Microglobulin And Hiv-Rt Variant Peptide I1y
	1I1Y	MHC+Peptide	Crystal Structure Of Human Class I Mhc (Hla-A2.1) Complexed With Beta 2-Microglobulin And Hiv-Rt Variant Peptide I1y
HLA-A6	1QRN	MHC+PEPTIDE+TCR	Crystal Structure Of Human A6 Tcr Complexed With Hla-A2 Bound To Altered Htlv-1 Tax Peptide P6a
HLA-Aw68.1	1HSB	MHC Only	Histocompatibility Antigen
HLA-B*0801	1AGB	MHC+Peptide	Antagonist Hiv-1 Gag Peptides Induce Structural Changes In Hla B8 - Hiv-1 Gag Peptide (Ggrkkykl - 3r Mutation)
	1AGC	MHC+Peptide	Antagonist Hiv-1 Gag Peptides Induce Structural Changes In Hla B8 - Hiv-1 Gag Peptide (Ggkkkyql - 7q Mutation)
	1AGD	MHC+Peptide	Antagonist Hiv-1 Gag Peptides Induce Structural Changes In Hla B8 - Hiv-1 Gag Peptide (Ggkkkykl - Index Peptide)
	1AGE	MHC+Peptide	Antagonist Hiv-1 Gag Peptides Induce Structural Changes In Hla B8 - Hiv-1 Gag Peptide (Ggkkkyrl - 7r Mutation)
	1AGF	MHC+Peptide	Antagonist Hiv-1 Gag Peptides Induce Structural Changes In Hla B8 - Hiv-1 Gag Peptide (Ggkkrykl - 5r Mutation)
HLA-B*3501	1A1N	MHC+Peptide	Mhc Class I Molecule B3501 Complexed With Peptide Vplrpmty From The Nef Protein (75-82) Of Hiv1
	1A9B	MHC+Peptide	Decamer-Like Conformation Of A Nano-Peptide Bound To Hla-B 3501 Due To Nonstandard Positioning Of The C-Terminus
	1A9E	MHC+Peptide	Decamer-Like Conformation Of A Nano-Peptide Bound To Hla-B 3501 Due To Nonstandard Positioning Of The C-Terminus
HLA-B*5101	1E27	MHC+Peptide	Nonstandard Peptide Binding Of Hla-B5101 Complexed With Hiv Immunodominant Epitope Km1(Lppvvakei)
HLA-B*5101	1E28	MHC+Peptide	Nonstandard Peptide Binding Of Hla-B5101 Complexed With Hiv Immunodominant Epitope Km2(Taftipsi)
HLA-B*5301	1A1M	MHC+Peptide	Mhc Class I Molecule B5301 Complexed With Peptide Typdinqml From Gag Protein Of Hiv2
HLA-B*5301	1A1O	MHC+Peptide	Mhc Class I Molecule B5301 Complexed With Peptide Ls6 (Kpivqydnf) From The Malaria Parasite P. Falciparum
HLA-Cw3	1EFX	MHC+PEPTIDE+TCR	Structure Of A Complex Between The Human Natural Killer Cell Receptor Kir2dl2 And A Class I Mhc Ligand Hla-Cw3
HLA-Cw4	1IM9	MHC+PEPTIDE+TCR	Crystal Structure Of The Human Natural Killer Cell Inhibitory Receptor Kir2dl1 Bound To Its Mhc Ligand Hla-Cw4
HLA-DM	1HDM	MHC Only	Histocompatibility Antigen Hla-Dm
HLA-E	1MHE	MHC Only	The Human Non-Classical Major Histocompatibility Complex Molecule Hla-E
Hla-Aw68	1TMC	MHC+Peptide	Truncated Human Class I Histocompatibility Antigen Hla-Aw68 Complexed With A Decameric Peptide (Evappeyhrk)
HLA-B*2705	1HSA	MHC Only	Histocompatibility Antigen
	1ROG	MHC+Peptide	Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes.Theoretical Model
	1ROH	MHC+Peptide	Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes.Theoretical Model
	1ROI	MHC+Peptide	Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes.Theoretical Model
	1ROJ	MHC+Peptide	Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes. Theoretical Model
	1ROK	MHC+Peptide	Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes. Theoretical Model
	1ROL	MHC+Peptide	Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes.Theoretical Model
Mic-1	1B3J	MHC+PEPTIDE+TCR	Structure Of The Mhc Class I Homolog Mic-A, A Gammadelta T Cell Ligand
Mica	1HYR	MHC+PEPTIDE+TCR	Crystal Structure Of Human Mica In Complex With Natural Killer Cell Receptor Nkg2d

Human (MHC Class II) TOP

MHC Allele PDB Code Structure Type PDB Title/Header

HLA-DR 1HQR MHC+Peptide Crystal Structure Of A Superantigen Bound To The High- Affinity, Zinc-Dependent Site On Mhc Class II

1IIE MHC+Peptide Mhc Class II-Associated Invariant Chain (II) Human Ectoplasmic Trimerization Domain

HLA-DR1 1KG0 MHC+Peptide Structure Of The Epstein-Barr Virus Gp42 Protein Bound To The Mhc Class II Receptor Hla-Dr1

1SEB MHC+Superantigen Complex Of The Human Mhc Class II Glycoprotein Hla-Dr1 and The Bacterial Superantigen Seb

1AQD MHC+Peptide Hla-Dr1 (Dra, Drb1 0101) Human Class II Histocompatibility Protein (Extracellular Domain) Complexed With Endogenous Peptide

1FYT MHC+PEPTIDE+TCR Crystal Structure Of A Complex Of A Human Alpha beta-T Cell Receptor, Influenza Ha Antigen Peptide, And Mhc Class II Molecule, Hla-Dr1

1HXY MHC+Peptide Crystal Structure Of Staphylococcal Enterotoxin H In Complex With Human Mhc Class II

HLA-DRB*0101 1DLH MHC+Peptide Hla-Dr1 (Dra, Drb1 0101) Human Class II Histocompatibility Protein (Extracellular Domain) Complexed With Antigenic Peptide

HLA-DRA*0101/DRB5*0101 1H15 MHC+Peptide X-Ray Crystal Structure Of Hla-Dra1*0101/Drb5*0101 Complexed With A Peptide From Epstein Barr Virus DNA Polymerase Classification Complex (Mhc/Antigen)

HLA-DR2 1FV1 MHC+Peptide Structural Basis For The Binding Of An Immunodominant Peptide From Myelin Basic Protein In Different Registers By Two Hla-Dr2 Alleles

HLA-DR3 1A6A MHC+Peptide The Structure Of An Intermediate In Class II Mhc Maturation: Clip Bound To Hla-Dr3

HLA-DR4 1D5M MHC+Peptide X-Ray Crystal Structure Of Hla-Dr4 Complexed With Peptide And Seb

1J8H MHC+Peptide+TCR Crystal Structure Of A Complex Of A Human alpha/ß-T Cell Receptor, Influenza Ha Antigen Peptide, and Mhc Class II Molecule, Hla-Dr4

1D5X MHC+Peptide X-Ray Crystal Structure Of Hla-Dr4 Complexed With Dipeptide Mimetic And Seb

1D6E MHC+Peptide Crystal Structure Of Hla-Dr4 Complex With Peptidomimetic And Seb

2SEB MHC+Peptide X-Ray Crystal Structure Of Hla-Dr4 Complexed With A Peptide From Human Collagen II

1D5Z MHC+Peptide X-Ray Crystal Structure Of Hla-Dr4 Complexed With Peptidomimetic And Seb

HLA-Dq8 1JK8 MHC+Peptide Crystal Structure Of A Human Insulin Peptide-Hla-Dq8 Complex

Mouse (MHC Class I) TOP

MHC Allele PDB Code Structure Type PDB Title/Header

H-2Db 1JPG MHC+Peptide Crystal Structure Of The Lcmv Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db

1JUF MHC+Peptide Structure Of Minor Histocompatibility Antigen Peptide, H13B, Complexed To H2-Db

1JPF MHC+Peptide Crystal Structure Of The Lcmv Peptidic Epitope Gp276 In Complex With The Murine Class I Mhc Molecule H-2Db

1FG2 MHC+Peptide Crystal Structure Of The Lcmv Peptidic Epitope Gp33 In Complex With The Murine Class I Mhc Molecule H-2db

1INQ MHC+Peptide Structure Of Minor Histocompatibility Antigen Peptide, H13A, Complexed To H2-db

1BZ9 MHC+Peptide Crystal Structure Of Murine Class I Mhc H2-Db Complexed With A Synthetic Peptide P1027

1CE6 MHC+Peptide Mhc Class I H-2db Complexed With A Sendai Virus Nucleoprotein Peptide

1QLF MHC+Peptide Mhc Class I H-2db Complexed With Glycopeptide K3g

H2-Dd 1BII MHC+Peptide The Crystal Structure Of H-2dd Mhc Class I In Complex With The Hiv-1 Derived Peptide P18-110

1DDH MHC+Peptide Mhc Class I H-2dd Heavy Chain Complexed With Beta-2 Microglobulin And An Immunodominant Peptide P18-I10 From The Human Immunodeficiency Virus Envelope Glycoprotein 120

1QO3 MHC+PEPTIDE+TCR Complex Between Nk Cell Receptor Ly49a And Its Mhc Class I Ligand H-2dd

H-2Kb 1KBG MHC+Peptide Mhc Class I H-2kb Presented Glycopeptide Rgy8-6h-Gal2

1KJ2 MHC+Peptide+TCR Murine Alloreactive Scfv Tcr-Peptide-Mhc Class I Molecule Complex

1LEG MHC+Peptide+TCR Crystal Structure Of H-2Kb Bound To The Dev8 Peptide

1NAM MHC+Peptide+TCR Murine Alloreactive Scfv Tcr-Peptide-Mhc Class I Molecule Complex

1MWA MHC+Peptide+TCR 2C/H-2Kbm3/Dev8 Allogeneic Complex

1KJ3 MHC+Peptide Mhc Class I H-2Kb Molecule Complexed With Pkb1 Peptide

1FZJ MHC+Peptide Mhc Class I Natural Mutant H-2kbm1 Heavy Chain Complexed With Beta-2 Microglobulin And Vesicular Stomatitis Virus Nucleoprotein

1FZK MHC+Peptide Mhc Class I Natural Mutant H-2kbm1 Heavy Chain Complexed With Beta-2 Microglobulin And Sendai Virus Nucleoprotein

1VAC MHC+Peptide Mhc Class I H-2kb Heavy Chain Complexed With Beta-2 Microglobulin And Chicken Ovalbumin

1FO0 MHC+PEPTIDE+TCR Murine Alloreactive Scfv Tcr-Peptide-Mhc Class I Molecule Complex

1OSZ MHC+Peptide Mhc Class I H-2kb Heavy Chain Complexed With Beta-2 Microglobulin And An (L4v) Mutant Of The Vesicular Stomatitis Virus Nucleoprotein

1VAD MHC+Peptide Mhc Class I H-2kb Heavy Chain Complexed With Beta-2 Microglobulin And Yeast Alpha-Glucosidase

2CKB MHC+Peptide Structure Of The 2ckbdev8 Complex

2VAA MHC+Peptide Mhc Class I H-2kb Heavy Chain Complexed With Beta-2 Microglobulin And Vesicular Stomatitis Virus Nucleoprotein

2VAB MHC+Peptide Mhc Class I H-2kb Heavy Chain Complexed With Beta-2 Microglobulin And Sendai Virus Nucleoprotein

1FZO MHC+Peptide Mhc Class I Natural Mutant H-2kbm8 Heavy Chain Complexed With Beta-2 Microglobulin And Sendai Virus Nucleoprotein

1FZM MHC+Peptide Mhc Class I Natural Mutant H-2kbm8 Heavy Chain Complexed With Beta-2 Microglobulin And Vesicular Stomatitis Virus Nucleoprotein

H-2Ld 1LD9 MHC+Peptide The Three-Dimensional Structure Of An H-2ld Peptide Complex Explains The Unique Interaction Of Ld With Beta2m And Peptide

1LDP MHC+Peptide Crystal Structure Of Murine Mhc Class I H-2ld With A Mixture Of Bound Peptides

H2-M3 1MHC MHC+Peptide Model Of Mhc Class I H2-M3 With Nonapeptide From Rat Nd1 Refined At 2.3 Angstroms Resolution

Qa-2 1K8D MHC+Peptide Crystal Structure Of The Non-Classical Mhc Class Ib Qa-2 Complexed With A Self Peptide

Mouse (MHC Class II) TOP Crystal Structure Of Class II Mhc Molecule Iab Bound To Ealpha3K Peptide

MHC Allele PDB Code Structure Type PDB Title/Header

I-AG7 1ES0 MHC+Peptide Crystal Structure Of The Murine Class II Allele I-A(G7) Complexed With The Glutamic Acid Decarboxylase (Gad65) Peptide 207-220

1F3J MHC+Peptide Histocompatibility Antigen I-Ag7

I-Ab 1MUJ MHC+CLIP Crystal Structure Of Murine Class II Mhc I-Ab In Complex With A Human Clip Peptide

1LNU MHC+Peptide

I-Ad 1IAO MHC+Peptide Class II Mhc I-Ad In Complex With Ovalbumin Peptide 323-339

2IAD MHC+Peptide Class II Mhc I-Ad In Complex With An Influenza Hemagglutinin Peptide 126-138

I-Ak 1D9K MHC+PEPTIDE+TCR Crystal Structure Of Complex Between D10 Tcr And Pmhc I- Akca

1IAK MHC Only Histocompatibility Antigen I-Ak

I-E 1I3R MHC Only Crystal Structure Of A Mutant Iek Class II Mhc Molecule

I-Ek 1FNE MHC Only Histocompatibility Antigen

1FNG MHC Only Histocompatibility Antigen

1IEA MHC Only Histocompatibility Antigen

1IEB MHC Only Histocompatibility Antigen

1KTD MHC+Peptide Crystal Structure Of Class II Mhc Molecule Iek Bound To Pigeon Cytochrome C Peptide

1KT2 MHC+Peptide Crystal Structure Of Class II Mhc Molecule Iek Bound To Moth Cytochrome C Peptide

I-Au 1K2D MHC+Peptide Crystal Structure Of The Autoimmune Mhc Class II I-Au Complexed With Myelin Basic Protein 1-11 At 2.2A

Others TOP

MHC Allele PDB Code Structure Type PDB Title/Header

Rt1-Aa 1ED3 MHC+Peptide Crystal Structure Of Rat Minor Histocompatibility Antigen Complex Rt1-Aamtf-E.

Beta-2-Microglobulin 1BMG MHC Only Crystal Structure Of Bovine Beta=2=-Microglobulin

H2-Dm 1K8I H2-Dm Only Crystal Structure Of Mouse H2-Dm