OCA Atlas for 1JK8
1JK8 Immune System date Jul 11, 2001
title Crystal Structure Of A Human Insulin Peptide-Hla-Dq8 Complex
authors K.H.Lee, K.W.Wucherpfennig, D.C.Wiley
compound source
Molecule: Mhc Class II Hla-Dq8
Chain: A
Fragment: Alpha Chain (Dqa10301)
Engineered: Yes
 Organism_scientific: Homo Sapiens
Organism_common: Human
Expression_system: Spodoptera Frugiperda
Expression_system_common: Fall Armyworm
Expression_system_vector_type: Baculovirus

Molecule: Mhc Class II Hla-Dq8
Chain: B
Fragment: Beta Chain (Dqb10302)
Engineered: Yes
Organism_scientific: Homo Sapiens
Organism_common: Human
Expression_system: Spodoptera Frugiperda
Expression_system_common: Fall Armyworm
Expression_system_vector_type: Baculovirus

Molecule: Insulin B Peptide
Chain: C
Fragment: Peptide (9-Shlvealylvcgerg-23)
Engineered: Yes
Synthetic: Yes
Other_details: This Peptide Was Chemically Synthesized. The Sequence Of This Peptide Occurs Naturally In Humans (Homo Sapiens).
symmetry Space Group: P 1 21 1
R_factor 0.224
crystal
cell
length a length b length c angle alpha angle beta angle gamma
66.034 42.862 87.467 90.00 102.48 90.00
method X-Ray Diffractionresolution 2.40 Å
ligand NAGenzyme
Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (79 Kb) [Save to disk]
  • LPC: Ligand-Protein Contacts for 1JK8
  • CSU: Contacts of Structural Units for 1JK8
  • Likely Quarternary Molecular Structure file(s) for 1JK8
  • Structure Factors (r1jk8sf.ent.Z) 152 Kb
  • Retrieve 1JK8 in mmCIF format [Save to disk]
    • View 1JK8 in 3D
  • Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only)
  • FirstGlance in Chemscape Chime (Install Chime freeware) This is good for easiest viewing of basic structure.
  • RasMol (Install RasMol freeware) Here's help on how to use RasMol.
    • Visual 3D analysis of 1JK8
  • STING, shows the sequence and maps the locations of sequence residues or residue ranges onto the 3D structure.
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
    • Structure-derived information
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Fold representative 1jk8 from FSSP and Dali (Families of Structurally Similar Proteins)
    • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1jk8_A] [1jk8_B] [1jk8_C]
    • Other resources with information on 1JK8
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • MMDB (Entrez's Structure Database)
    • Movements, Movies and Images
  • Images from IMB Jena Image Library of Biological Macromolecules.

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