OCA Atlas for 1ROG
1ROG Histocompatibility Antigen date Jul 19, 1994
authors D.Rognan, L.Scapozza, G.Folkers, A.Daser
compound source
Class I Histocompatibility Antigen Hla-B2705 Complexed With Nonapeptide Arg-Arg-Ile-Lys-Ala-Ile-Thr-Leu-Lys (Theoretical Model)
Hla-B2705: Human (Homo Sapiens); Nonapeptide: Synthetic
methodTheoretical Model
ligand NMEenzyme
similarity Belongs to the MHC_I family.
subunit Dimer of alpha chain and a beta chain (beta-2- microglobulin).
genes HLA-B, HLAB (H. sapiens)
function Involved in the presentation of foreign antigens to the immune system.
Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (44 Kb) [Save to disk]
  • LPC: Ligand-Protein Contacts for 1ROG
  • CSU: Contacts of Structural Units for 1ROG
  • Likely Quarternary Molecular Structure file(s) for 1ROG
  • Retrieve 1ROG in mmCIF format [Save to disk]
  • View 1ROG in 3D
  • Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only)
  • FirstGlance in Chemscape Chime (Install Chime freeware) This is good for easiest viewing of basic structure.
  • RasMol (Install RasMol freeware) Here's help on how to use RasMol.
  • Visual 3D analysis of 1ROG
  • STING, shows the sequence and maps the locations of sequence residues or residue ranges onto the 3D structure.
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
  • GRASS (Graphical Representation and Analysis of Structure Server)
  • View 1ROG in 2D
  • Topology of domains/folds: Chain: A from TOPS (The Atlas of protein topology cartoons )
  • Structure-derived information
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Fold representative 1rog from FSSP and Dali (Families of Structurally Similar Proteins)
  • Domain Definition for 1rog from 3Dee ( The Database of Protein Domain Definitions )
  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1rog_A] [1rog_B]
  • SWISS-PROT database: [1B18_HUMAN]
  • Domain organization of [1B18_HUMAN] by SWISSPFAM
  • Conserved protein region description, domain view and alignment from family MHC_I (PF00129) of Pfam.
  • Alignments of the sequence of 1ROG with the sequences similar proteins can be viewed for classification [1B18_HUMAN] at ProtoMap. Click on "Neighbors List", then on the "See Alignments" button below the list.
  • A sequence distance tree ("phylogenetic tree") can be viewed for 1ACL's classification [1B18_HUMAN] at ProtoMap. Click on the Cluster number.
  • Other resources with information on 1ROG
  • InterPro: IPR003006 , IPR001039 , IPR003597
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • Movements, Movies and Images
  • Images from IMB Jena Image Library of Biological Macromolecules.

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