OCA Atlas for 1FYT
1FYT Immune System date Oct 03, 2000
title Crystal Structure Of A Complex Of A Human Alphabeta-T Cell Receptor, Influenza Ha Antigen Peptide, And Mhc Class II Molecule, Hla-Dr1
authors J.Hennecke, A.Carfi, D.C.Wiley
compound source
Molecule: Hla Class II Histocompatibility Antigen, Dr Alpha Chain;
Chain: A
Fragment: Extracellular Domain
Synonym: Hla-Dr1, Dra
Engineered: Yes
Organism_scientific: Homo Sapiens
Organism_common: Human
Expression_system: Drosophila Melanogaster
Expression_system_common: Fruit Fly

Molecule: Hla Class II Histocompatibility Antigen, Dr-1 Beta Chain;
Chain: B
Fragment: Extracellular Domain
Synonym: Hla-Dr1, Drb1 0101
Engineered: Yes

Organism_scientific: Homo Sapiens
Organism_common: Human
Expression_system: Drosophila Melanogaster
Expression_system_common: Fruit Fly

Molecule: Hemagglutinin Ha1 Peptide Chain
Chain: C
Fragment: Antigen Peptide
Engineered: Yes

Organism_scientific: Influenza Virus A
Expression_system: Escherichia Coli
Expression_system_common: Bacteria

Molecule: T-Cell Receptor Alpha Chain
Chain: D
Fragment: Extracellular Domain
Synonym: Tcr Ha1.7 Alpha Chain
Engineered: Yes

Organism_scientific: Homo Sapiens
Organism_common: Human
Expression_system: Escherichia Coli
Expression_system_common: Bacteria

Molecule: T-Cell Receptor Beta Chain
Chain: E
Fragment: Extracellular Domain
Synonym: Tcr Ha1.7 Beta Chain
Engineered: Yes
Mutation: Yes

Organism_scientific: Homo Sapiens
Organism_common: Human
Expression_system: Escherichia Coli
Expression_system_common: Bacteria
symmetry Space Group: C 1 2 1
R_factor 0.221
crystal
cell
length a length b length c angle alpha angle beta angle gamma
142.902 73.439 122.428 90.00 108.23 90.00
method X-Ray Diffractionresolution 2.60 Å
ligand NAGenzyme
Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (157 Kb) [Save to disk]
  • LPC: Ligand-Protein Contacts for 1FYT
  • CSU: Contacts of Structural Units for 1FYT
  • Likely Quarternary Molecular Structure file(s) for 1FYT
  • Structure Factors (r1fytsf.ent.Z) 400 Kb
  • Retrieve 1FYT in mmCIF format [Save to disk]
  • View 1FYT in 3D
  • Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only)
  • FirstGlance in Chemscape Chime (Install Chime freeware) This is good for easiest viewing of basic structure.
  • RasMol (Install RasMol freeware) Here's help on how to use RasMol.
  • Visual 3D analysis of 1FYT
  • STING, shows the sequence and maps the locations of sequence residues or residue ranges onto the 3D structure.
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
  • Structure-derived information
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Classification of representative domains in scop (Structural Classification of Proteins)
        - Domain d1fyta2, region A:2-81 [rasmolscript] [script source]
        - Domain d1fyta1, region A:82-181 [rasmolscript] [script source]
        - Domain d1fytb2, region B:3-92 [rasmolscript] [script source]
        - Domain d1fytb1, region B:93-190 [rasmolscript] [script source]
        - Domain d1fytd1, region D:1-117 [rasmolscript] [script source]
        - Domain d1fytd2, region D:118-203 [rasmolscript] [script source]
        - Domain d1fyte2, region E:119-246 [rasmolscript] [script source]
        - Domain d1fyte1, region E:3-118 [rasmolscript] [script source]
  • Fold representative 1fyt from FSSP and Dali (Families of Structurally Similar Proteins)
  • Class (fold), Architecture (subfold), Topology, Homologous superfamily: CATH
  • Summaries and structural analyses of PDB data files: PDBSum
  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1fyt_A] [1fyt_B] [1fyt_C] [1fyt_D] [1fyt_E]
  • Other resources with information on 1FYT
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • MMDB (Entrez's Structure Database)
  • Movements, Movies and Images
  • Images from IMB Jena Image Library of Biological Macromolecules.

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