Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 485
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1167HIV-env 848-863RHIPRRIRQGLERILL16LNoneNoneNoneLinearSyntheticNANANot AvailableIn vitroHuman seraNANANANANA24558991988
1168HIV-env 854-863IRQGLERILL10LNoneNoneNoneLinearSyntheticNANANot AvailableIn vitroHuman seraNANANANANA24558991988
1169CS-1 (HTLV-1)AQNRRGLDLLFWEQGGL17LNoneNoneNoneLinearSyntheticHTLV-I gp21ENANot AvailableIn vitroCTL-23 nmol/wellNANANANA29734361988
1170CS-3 (HIV)LQARILAVERYLKDQQL17LNoneNoneNoneLinearSyntheticHIV gp41NANot AvailableIn vitroCTL-23 nmol/wellNANANANA29734361988
1171CS-2 (Endogenous)YQNRLALDYLLAAEGGV17LNoneNoneNoneLinearSyntheticHuman genomic DNANANot AvailableIn vitroCTL-2NANANANANA29734361988
1172Spleen-derived immunosuppressive peptide (SDIP)not available0LNoneNoneNoneLinearNaturalBovin spleenNAInhibits the formation of 19 S antibody forming cellsBothBovine spleen extractNADBA/2 X C57BL/6 and Balb/cPlaque-forming cell (PFC) assayNANA72172771981
1173Cyclosporin Acyclo[Abu-Sar-N(Me)Leu-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]11MixNoneNoneBmt = butenyl-methyl-threonine, Abu = L-alpha-aminobutyric acid, Sar = sarcosine, N(Me) = Amino acid is N-methylatedCyclicNaturalFungusNANot AvailableIn vivoNANACBA/Ca and (CBA/Ca X C57BL6)F1 micePlaque-forming cell (PFC) assayNANA61594101980
1174Immunosuppressive peptidenot available0LNoneNoneNoneLinearProtein DerivedCohn fraction IV of normal human plasmaNASuppresses phytohemagglutinin induced lymphocyte proliferationBothHuman peripheral lymphocytesNAAdult mice (C57BL/6J or CBA)Phytohemagglutinin (PHA)-induced lymphocyte Proliferation assay and modified Jerne hemolytic plaque techniqueNANA45697991973
1175Immunoregulatory α-globulinnot available0LNoneNoneNoneLinearNaturalHuman SeraNANot AvailableBothHuman SeraNAAdult CD-l miceAssay for inhibition of PHA-induced ProliferationNANA41353101975
1176immunoregulatory a-globulin-like peptidenot available0LNoneNoneNoneLinearNaturalHuman SeraNANot AvailableBothHuman SeraNAAdult CD-l miceNANANA41353101975
1177Spleen-derived immunosuppressive peptide (SDIP)not available0LNoneNoneNoneLinearNaturalNot availableNANot AvailableBothSpleen CellsNABalb/c or (C57B1/6 x DBA2)Fl hybrids 8-10 weeks old.Cunningham technique, Mishell and Dutton technique, FTS radioimmunoassay, rosette assayNANA66820891983
1178Spleen-derived inhibiting peptide (SDIP)not available0LNoneNoneNoneLinearNaturalNot availableNANot AvailableBothSpleen cellsNA(DBA/2 X C57BL/6) strain or Balb/c strainPlaque-forming cell (PFC) assayNANA72262351981
1179Immunoglobulin-binding factor (IBF)not available0LNoneNoneNoneLinearNaturalNot availableNANot AvailableBothSpleen cellsNA(DBA/2 X C57BL/6) strain or Balb/c strainPlaque-forming cell (PFC) assayNANA72262351981
1180Immunosuppressive epitope of retroviral plSEnot available17LNoneNoneNoneLinearProtein DerivedRetroviral protein pl5EIL-2, TNF-α, protein kinase-CInhibits human mitogen and alloantigen-stimulated lymphocyte proliferation, natural killer cell activity, interleukin 1-mediated monocyte tumor killing, interleukin 2 production, immunoglobulin synthesis, TNF-α mRNA expression and protein kinase C activityBothU937, P2, JLS-V5NABALB/c mice (Female, 12- week-old)NANANA75110541994
1181CKS-17LONRRGLDLLFLKEGGL17LNoneNoneNoneLinearSyntheticNot availableNANot AvailableIn vitroU937, P2, JLS-V5NANANANANA75110541994
1182SMRV-H peptideEVVLQNRRGLDLLTAEQGGICLALQERCCFYANKS35DNoneNoneNoneLinearProtein DerivedSquirrel monkey retrovirus (SMRV)NANot AvailableIn vitroU937, P2, JLS-V5NANANANANA32017491988
1183SRV-1 peptideEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedSimian retrovirus type-1NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1184SRV-2 peptideEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedSimian retrovirus type-2NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1185MPMVEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedMason-Pfizer monkey virusNANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1186REV-AEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedReticuloendotheliosis-associated virus (REV-A)NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1187FeLVEVVLQNRRGLDILFLQEGGLCAALKEECCFYADHT35LNoneNoneNoneLinearProtein DerivedFeline leukemia virus (FeLV)NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1188Mo-MLVEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHT35LNoneNoneNoneLinearProtein DerivedMoloney murine leukemia virusNANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1189RSVHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDH35LNoneNoneNoneLinearProtein DerivedRespiratory syncytial virusNANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1190HTLV-1QYAAQNRRGLDLLFWEQGGLCKALQEQCRFPNITN35LNoneNoneNoneLinearProtein DerivedHuman T-cell lymphotropic virus 1NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1191HTLV-2QYAAQNRRGLDLLFWEQGGLCKALQEQCCFLNISN35LNoneNoneNoneLinearProtein DerivedHuman T-cell lymphotropic virus 2NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1192CKS-17LQNRRGLDLLFLKEGGL17LNoneNoneNoneLinearSyntheticNANANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1193SEQ ID NO:1ILNRKAIDFLLQRWGGT17LNoneNonepolyethylene glycol conjugatedLinearProtein DerivedZaire ebola virus, C-terminus domain of the envelope glycoproteinCD4+, CD8+ cellsDepletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 levelIn vitroPBMCNANANANApolyethylene glycol conjugatedUS 20070185025 A12007
1194SEQ ID NO:2LINRHAIDFLLTRWGGT17LNoneNonepolyethylene glycol conjugatedLinearProtein DerivedLake Victoria marburg virusCD4+, CD8+ cellsDepletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 levelIn vitroPBMCNANANANApolyethylene glycol conjugatedUS 20070185025 A12007
1195SEQ ID NO:3ILNRKAIDFLLRRWGGT17LNoneNonepolyethylene glycol conjugatedLinearProtein DerivedSudan ebola virus,C-terminus domain of the envelope glycoproteinCD4+, CD8+ cellsDepletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 levelIn vitroPBMCNANANANApolyethylene glycol conjugatedUS 20070185025 A12007
1196SEQ ID NO:4LLNRKAIDFLLQRWGGT17LNoneNonepolyethylene glycol conjugatedLinearProtein DerivedReston ebola virus, C-terminus domain of the envelope glycoproteinCD4+, CD8+ cellsDepletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 levelIn vitroPBMCNANANANApolyethylene glycol conjugatedUS 20070185025 A12007
1197SEQ ID NO:5ILNRKAIDFLLQRWGGT17LNoneNonepolyethylene glycol conjugatedLinearProtein DerivedIvory coast ebola virus, C-terminus domain of the envelope glycoproteinCD4+, CD8+ cellsDepletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 levelIn vitroPBMCNANANANApolyethylene glycol conjugatedUS 20070185025 A12007
1198SEQ ID NO 1VVGGYNCEMNSQVAVYYFGEYLC26LNoneNoneNoneLinearNaturalRattus rattusNAAffecting lymph node cell proliferationIn vivoNANAMice, DTH model, CA modelContact sensitivity in miceNANAUS 7195759 B22007
1199LffX-IVGINVKCKHSRQCLKPCKDAGMRFGKCTNGKCHCTPK37LNoneNoneNoneLinearNaturalScorpion venomKv1.3 potassium channels of T cellshigh specificity binding Kv1.3 potassium channels of T cellsBothC0S-7 cells1.08 pMArthritic Lewis rats, EAE model of Wistar ratsNANANACN 101423550 B2012
1200LWX-AD-1NEAVPTGGCPFSDFFCAKRCKDMKFGNTGRCTGPNKTVCKCSI43LNoneNoneNoneLinearNaturalScorpion venomKv1.3 potassium channels of T cellshigh specificity binding Kv1.3 potassium channels of T cellsBothC0S-7 cells0.52 nMArthritic Lewis rats, EAE model of Wistar ratsNANANACN 101423550 B2012
120111R-VEETRRRRRRRRRRRMAGPHPVIVITGPHEE27LNoneNoneNoneLinearSyntheticNAT cells, Transcription of IL-2 geneSuppressive agent of NFAT activationBothJurkatNABALB/c mouse, H-2d mouse, C3H/HeN mouse H-2kNANANAUS 7659249 B22010
1202A1HS1II-Sta-PYVPL8LNoneNoneSta = (3S, 4S) -4- amino-3-hydroxy-6-methyl-heptanoic acid(C8H17NO3)CyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289499 B2010
1203A3HS1IIPPYV-Sta-L8LNoneNoneSta = StatineCyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289498 B2010
1204A4HS1II-Sta-Sta-YVPL8LNoneNoneSta = StatineCyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289497 A2008
1205NALQNRRGLDILFLQEGGLC18LNoneNoneNoneLinearSyntheticRetro virus, Feline leukemia virus (FLV)NAInhibiting T-cell proliferationIn vitroSpleen cellsNAMurine (C57BL/6 strain)Inhibition of Concanavalin A-induced T-cell Proliferation of murineNANAWO 1988005783 A11988
1206NAAALKEECCFLKEEC14LNoneNoneNoneLinearSyntheticRetro virusT-cellsInhibiting T-cell proliferationIn vitroSpleen cellsNAMurine (C57BL/6 strain)Inhibition of Concanavalin A-induced T-cell Proliferation of murineNANAWO 1988005783 A11988
1207NAQEGGLCAALKEEC13LNoneNoneNoneLinearSyntheticRetro virusT-cellsInhibiting T-cell proliferationIn vitroSpleen cellsNAMurine (C57BL/6 strain)Inhibition of Concanavalin A-induced T-cell Proliferation of murineNANAWO 1988005783 A11988
1208NAQREKRAVGIGALFLGFLG18LNoneNoneNoneLinearSyntheticRetro virusT-cellsInhibiting T-cell proliferationIn vitroSpleen cellsNAMurine (C57BL/6 strain)Inhibition of Concanavalin A-induced T-cell Proliferation of murineNANAWO 1988005783 A11988
1209NAQLTVWGIKQLQARIL15LNoneNoneNoneLinearSyntheticRetro virusT-cellsInhibiting T-cell proliferationIn vitroSpleen cellsNAMurine (C57BL/6 strain)Inhibition of Concanavalin A-induced T-cell Proliferation of murineNANAWO 1988005783 A11988
1210NAAQNRRGLDLLFWEQGGLC18LNoneNoneNoneLinearSyntheticRetro virusT-cellsInhibiting T-cell proliferationIn vitroSpleen cellsNAMurine (C57BL/6 strain)Inhibition of Concanavalin A-induced T-cell Proliferation of murineNANAWO 1988005783 A11988
1211NAHAwY4MixNoneNoneA-D-Glu or D-iGlu, Y-OH or a substituted amide(C1-C3)LinearNaturalTotal tissue extractsBone marrow cells, Hematopoietic progenitor cellsReduces amount of ekzokolony cells, reduce KOE-C pool sizesBothHematopoietic progenitor Cells from miceNAMiceNANANARU2123859 (C1)1998
1212SEQ ID NO: 1ILAKFLHWL9LNoneNoneInventors midified C- or at the N-terminus of the peptides with stabilizing groups, groups for increasing the water solubility, luminescent markers, fluorescent markers, radioactive markers, metal markers, polymeric markers, antibodies, enzymes, epitope tags, amino acid, D- or L-amino acids, serine, glycine, aspartate, sugar groups, glucuronic acid, sulfate moieties and polyethylene glycol. for experimentsLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANADE 102006025146 A12007
1213SEQ ID NO: 2AEHRLREEILAKFLHWLMSVYVVEL25LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1214SEQ ID NO: 3MLMYILAKFLHWLGGYILAKFLHWLGGYILAKFLHWL37LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1215SEQ ID NO: 4RLMYDILAKFLHWLGPSEKRVWMS24LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1216SEQ ID NO: 5AHGVILAKFLHWLSTAPPAHGVILAKFLHWLSTAPPA37LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007