Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 485
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1217SEQ ID NO: 6QMNLILAKFLHWLCMTWNQMNLILAKFLHWLCMTW35LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1218SEQ ID NO: 7RLMYILAKFLHWLGPSRLMYILAKFLHWLGPS32LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1219SEQ ID NO: 8VHNVILAKFLHWLSTAPPVHNVILAKFLHWLSTAPPV37LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1220NACVRGLYIDFRKDLGWK16LNoneNoneNoneLinearSyntheticRetro virusLymphocytes, TGFInhibits cell proliferation, conjugated polypeptide block the binding of TGF-B to its receptorBothMu-I-LvNADBA/IJ male miceThymidine incorporation assay, TGF-fi Radioreceptor Binding Assay, Mice arthritis modelNACoupled to carrier proteins or crosslinked to form polymersCA2057896C2000
1221Aalpha (SEQ ID NO 12)ERHQSACKDSDWPFCSDEDWNYK23LNoneNoneNoneLinearProtein DerivedAlpha chain of the fibrinLymphocyteSuppress increase in inflammatory cells, Aalpha Gly Pro Arg (Pro) - NH 2 acetate (Aalpha derivative) short peptide is equally effective as the long peptides in appropriate continuous addition at inhibiting monocyte migrationIn vivoPBMCNAHU-SCID mouse modelNANANAWO 2002048180 A22002
1222Bbeta (SEQ ID NO 11)DKRKEEAPSLRPAPPPISGGGYR23LNoneNoneNoneLinearProtein DerivedBeta chain of the fibrinLymphocyteInhibition of Lymphocyte migration, blocks the lymphocytic inflammation, Bbeta Gly His Arg Pro-OH acetate (Bbeta derivative) short peptide is equally effective as the long peptides in appropriate continuous addition at inhibiting monocyte migrationIn vivoPBMCNAHU-SCID mouse modelNANANAWO 2002048180 A22002
1223sequence no 4HFKRPLPPLPSL12LNoneNoneNoneLinearSyntheticNAT-cell, Hematopoietic cellHuman T-cell tyrosine kinase (Lck) inhibitor, Hematopoietic cell kinase (Hck) inhibitorIn vitroNANANALck-SH3 binding assay, NMR Spectroscopy, protein-protein interactions assay by PepSpot membranesNANAEP 1983050 A12008
1224SEQ ID NO:60LVCYYTSWS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1225SEQ ID NO:61FLCTHIIYS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1226SEQ ID NO:62IIYSFANIS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1227SEQ ID NO:63LKTLLSVGG9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1228SEQ ID NO:64FIKSVPPFL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1229SEQ ID NO:65FDGLDLAWL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1230SEQ ID NO:66LYPGRRDKQ9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1231SEQ ID NO:67YDIAKISQH9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1232SEQ ID NO:68LDFISIMTY9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1233SEQ ID NO:69FISIMTYDF9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1234SEQ ID NO:70FRGQEDASP9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1235SEQ ID NO:71YAVGYMLRL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1236SEQ ID NO:72MLRLGAPAS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1237SEQ ID NO:73LAYYEICDF9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1238SEQ ID NO:74LRGATVHRT9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1239SEQ ID NO:75YLKDRQLAG9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1240SEQ ID NO:76LAGAMVWAL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1241SEQ ID NO:77VWALDLDDF9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1242SEQ ID NO:78LDLDDFQGS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1243SEQ ID NO:lYKLVCYYTSWSQYREG16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1244SEQ ID NO:2YTSWSQYREGDGSCFP16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1245SEQ ID NO:5LDRFLCTHIIYSFANI16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1246SEQ ID NO:6THIIYSFANISNDHID16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1247SEQ ID NO:12PNLKTLLSVGGWNFGS16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1248SEQ ID NO:16NTQSRRTFIKSVPPFL16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1249SEQ ID NO:17TFIKSVPPFLRTHGFD16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1250SEQ ID NO:18PPFLRTHGFDGLDLAW16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1251SEQ ID NO:19HGFDGLDLAWLYPGRR16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1252SEQ ID NO:20DLAWLYPGRRDKQHFT16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1253SEQ ID NO:28IDSSYDIAKISQHLD16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1254SEQ ID NO:29DIAKISQHLDFISIMT16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1255SEQ ID NO:30QHLDFISIMTYDFHGA16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1256SEQ ID NO:34SPLFRGQEDASPDRFS16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1257SEQ ID NO:37DYAVGYMLRLGAPASK16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1258SEQ ID NO:38MLRLGAPASKLVMGIP16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1259SEQ ID NO:39PASKLVMGIPTFGRSF16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1260SEQ ID NO:46GTLAYYEICDFLRGAT16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1261SEQ ID NO:47EICDFLRGATVHRTLG16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1262SEQ ID NO:48RGATVHRTLGQQVPYA16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1263SEQ ID NO:53VKSKVQYLKDRQLAGA16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1264SEQ ID NO:54YLKDRQLAGAMVWALD16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1265SEQ ID NO:55LAGAMVWALDLDDFQG16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1266SEQ ID NO:56WALDLDDFQGSFCGQD16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997