Primary information |
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ID | 1260 |
Peptide Name | SEQ ID NO:46 |
Sequence | GTLAYYEICDFLRGAT |
Length | 16 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Protein Derived |
Source of Origin | Human Cartilage glycoprotein 39 |
Target | T-cells |
Mechanism of Action | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact |
In vitro/In vivo | In vitro |
Cell Line | PBMC |
Inhibition Concentartion | NA |
In vivo Model | NA |
Assay | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | WO 1997040068 A1 |
Year of Publication | 1997 |
3-D Structure | View in Jmol or Download Structure |