| Primary information |
|---|
| ID | 1260 |
| Peptide Name | SEQ ID NO:46 |
| Sequence | GTLAYYEICDFLRGAT |
| Length | 16 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Protein Derived |
| Source of Origin | Human Cartilage glycoprotein 39 |
| Target | T-cells |
| Mechanism of Action | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact |
| In vitro/In vivo | In vitro |
| Cell Line | PBMC |
| Inhibition Concentartion | NA |
| In vivo Model | NA |
| Assay | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | WO 1997040068 A1 |
| Year of Publication | 1997 |
| 3-D Structure |  View in Jmol or Download Structure |
