| Primary information |
|---|
| ID | 1220 |
| Peptide Name | NA |
| Sequence | CVRGLYIDFRKDLGWK |
| Length | 16 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Synthetic |
| Source of Origin | Retro virus |
| Target | Lymphocytes, TGF |
| Mechanism of Action | Inhibits cell proliferation, conjugated polypeptide block the binding of TGF-B to its receptor |
| In vitro/In vivo | Both |
| Cell Line | Mu-I-Lv |
| Inhibition Concentartion | NA |
| In vivo Model | DBA/IJ male mice |
| Assay | Thymidine incorporation assay, TGF-fi Radioreceptor Binding Assay, Mice arthritis model |
| Lethal Dose | NA |
| Combination Therapy | Coupled to carrier proteins or crosslinked to form polymers |
| Pubmed ID | CA2057896C |
| Year of Publication | 2000 |
| 3-D Structure |  View in Jmol or Download Structure |
