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1222 details |
| Primary information | |
|---|---|
| ID | 1222 |
| Peptide Name | Bbeta (SEQ ID NO 11) |
| Sequence | DKRKEEAPSLRPAPPPISGGGYR |
| Length | 23 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Protein Derived |
| Source of Origin | Beta chain of the fibrin |
| Target | Lymphocyte |
| Mechanism of Action | Inhibition of Lymphocyte migration, blocks the lymphocytic inflammation, Bbeta Gly His Arg Pro-OH acetate (Bbeta derivative) short peptide is equally effective as the long peptides in appropriate continuous addition at inhibiting monocyte migration |
| In vitro/In vivo | In vivo |
| Cell Line | PBMC |
| Inhibition Concentartion | NA |
| In vivo Model | HU-SCID mouse model |
| Assay | NA |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | WO 2002048180 A2 |
| Year of Publication | 2002 |
| 3-D Structure |  View in Jmol or Download Structure |