| Primary information |
|---|
| ID | 1173 |
| Peptide Name | Cyclosporin A |
| Sequence | cyclo[Abu-Sar-N(Me)Leu-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)] |
| Length | 11 |
| Chirality | Mix |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | Bmt = butenyl-methyl-threonine, Abu = L-alpha-aminobutyric acid, Sar = sarcosine, N(Me) = Amino acid is N-methylated |
| Linear/ Cyclic | Cyclic |
| Nature | Natural |
| Source of Origin | Fungus |
| Target | NA |
| Mechanism of Action | Not Available |
| In vitro/In vivo | In vivo |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| In vivo Model | CBA/Ca and (CBA/Ca X C57BL6)F1 mice |
| Assay | Plaque-forming cell (PFC) assay |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | 6159410 |
| Year of Publication | 1980 |
| 3-D Structure | NA |
