The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_568	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with PKA catalytic subunit siRNA and scramble siRNA (siPKA-1)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	62% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27374176
OV_569	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with PKA catalytic subunit siRNA and scramble siRNA (siPKA-2)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	57% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27374176
OV_570	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with PKA catalytic subunit siRNA and scramble siRNA (siPKA-3)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	65% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27374176
OV_571	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	10 PFU/cell	50% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_572	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.001 PFU/cell	70% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_573	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.001 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_574	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.01 PFU/cell	39% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_575	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.01 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_576	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.1 PFU/cell	22% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_577	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.1 PFU/cell	92% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_578	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	1 PFU/cell	20% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_579	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	1 PFU/cell	80% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_580	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	20% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_581	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	10 PFU/cell	75% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_582	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.001 PFU/cell	86% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_583	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.001 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_584	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.01 PFU/cell	80% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_585	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.01 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_586	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	0.1 PFU/cell	70% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_587	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	0.1 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_588	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	1 PFU/cell	38% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_589	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	1 PFU/cell	90% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_590	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89(10 μM) for 1 hour	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	25% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_591	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	Non toxic to human immortalized liver cell line L-02	MTT assay	10 PFU/cell	80% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_592	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1001)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	100% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_593	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1002)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	70% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_594	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1003)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	90% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	NA	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_595	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1001) and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	60% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_596	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1002) and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	45% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_597	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with small interfering RNA (siRNAs) against Epac1 (siEpac1003) and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	Very small toxicity towards human immortalized liver cell line L-02	MTT assay	10 PFU/cell	75% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	JNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activated	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_598	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with ESI-09 and with H89(10 μM)	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	0.1 PFU/cell	60% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	ESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_599	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with ESI-09	No	ATCC	Human colorectal carcinoma cell line	HCT-116	4000 cells per well	NA	MTT assay	0.1 PFU/cell	80% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	ESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_600	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with ESI-09 and with H89(10 μM)	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.1 PFU/cell	75% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	ESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.	M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89	NA	27374176
OV_601	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with ESI-09	No	ATCC	Human pancreatic ductal adenocarcinoma cell line	Capan-1	4000 cells per well	NA	MTT assay	0.1 PFU/cell	82% cancer cell viability at 72 hours post-infection	No	No	NA	No response	NA	ESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.	M1 upregulated transcriptional ISGs (329 shown here)	NA	27374176
OV_602	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89 (10 mg/kg/d), injected intraperitoneally	No	NA	NA	NA	NA	NA	NA	NA	NA	Female BALB/c-nu/nu mice inoculated subcutaneously with HCT-116, 5.0E+6 cells per mouse	3.0E+7 PFU/d	NA	Reduction in tumor volume to 0.2 cubic centimeter compared to control 1cubic centimeter after 27 days	intravenously	Activates Caspase-3	NA	NA	27374176
OV_603	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Female BALB/c-nu/nu mice inoculated subcutaneously with HCT-116, 5.0E+6 cells per mouse	3.0E+7 PFU/d	NA	Reduction in tumor volume to 0.76 cubic centimeter compared to control 1cubic centimeter after 27 days	intravenously	Activates Caspase-3 (very small)	NA	NA	27374176
OV_604	Alphavirus	M1	RNA	Togaviridae	None	No	Viral strain in combination with H89 (10 mg/kg/d), injected intraperitoneally	No	NA	NA	NA	NA	NA	NA	NA	NA	Female BALB/c-nu/nu mice inoculated subcutaneously with Capan-1, 3.0E+6 cells per mouse	3.0E+7 PFU/d	NA	Reduction in tumor volume to 0.1 cubic centimeter compared to control 1cubic centimeter after 23 days	intravenously	Activates Caspase-3	NA	NA	27374176
OV_605	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Female BALB/c-nu/nu mice inoculated subcutaneously with Capan-1, 3.0E+6 cells per mouse	3.0E+7 PFU/d	NA	Reduction in tumor volume to 0.2 cubic centimeter compared to control 1cubic centimeter after 23 days	intravenously	Activates Caspase-3 (very small)	NA	NA	27374176
OV_4275	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human melanoma cell line	B16	4000 cells per well	NA	MTT assay	10 pfu	2.19 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4276	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	4000 cells per well	NA	MTT assay	10 pfu	3.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4277	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	LoVo	4000 cells per well	NA	MTT assay	10 pfu	6.9 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4278	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder squamous cell carcinoma cell line	SCaBER	4000 cells per well	NA	MTT assay	10 pfu	11.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4279	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human cervix carcinoma	C33A	4000 cells per well	NA	MTT assay	10 pfu	14.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4280	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder transitional cell carcinoma	T24	4000 cells per well	NA	MTT assay	10 pfu	21.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4281	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human nasopharyngeal carcinoma	CNE-2	4000 cells per well	NA	MTT assay	10 pfu	24.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4282	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human breast carcinoma	4T1	4000 cells per well	NA	MTT assay	10 pfu	26.27 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4283	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human glioblastoma	C6	4000 cells per well	NA	MTT assay	10 pfu	31.4 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4284	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	U-87 MG	4000 cells per well	NA	MTT assay	10 pfu	32.4 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4285	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human glioblastoma	U251	4000 cells per well	NA	MTT assay	10 pfu	34.7 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4286	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma	HCT-8	4000 cells per well	NA	MTT assay	10 pfu	35.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4287	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma multiforme	T98G	4000 cells per well	NA	MTT assay	10 pfu	38.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4288	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate carcinoma	22Rv1	4000 cells per well	NA	MTT assay	10 pfu	39.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4289	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder transitional cell carcinoma	UM-UC-3	4000 cells per well	NA	MTT assay	10 pfu	39.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4290	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	U-138 MG	4000 cells per well	NA	MTT assay	10 pfu	40.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4291	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma	SW620	4000 cells per well	NA	MTT assay	10 pfu	43.7 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4292	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human breast carcinoma	MDA-MB-468	4000 cells per well	NA	MTT assay	10 pfu	43.7 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4293	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas epithelioid carcinoma	SW1990	4000 cells per well	NA	MTT assay	10 pfu	45.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4294	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human skin malignant melanoma	A375	4000 cells per well	NA	MTT assay	10 pfu	47.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4295	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human nasopharyngeal carcinoma	CNE-1	4000 cells per well	NA	MTT assay	10 pfu	48.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4296	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas carcinoma	MIAPaCa-2	4000 cells per well	NA	MTT assay	10 pfu	49.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4297	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas epithelioid carcinoma	PANC-1	4000 cells per well	NA	MTT assay	10 pfu	49.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4298	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder carcinoma	5637	4000 cells per well	NA	MTT assay	10 pfu	50.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4299	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma	Huh-7	4000 cells per well	NA	MTT assay	10 pfu	52.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4300	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma	SW480	4000 cells per well	NA	MTT assay	10 pfu	53.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4301	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human breast adenocarcinoma	MDA-MB-231	4000 cells per well	NA	MTT assay	10 pfu	58.9 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4302	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatoblastoma	Huh-6	4000 cells per well	NA	MTT assay	10 pfu	59 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4303	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human glioma	MGR2	4000 cells per well	NA	MTT assay	10 pfu	63.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4304	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human cervix adenocarcinoma	HeLa	4000 cells per well	NA	MTT assay	10 pfu	66 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4305	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human lung carcinoma	A549	4000 cells per well	NA	MTT assay	10 pfu	68.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4306	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human liver adenocarcinoma	SK-HEP-1	4000 cells per well	NA	MTT assay	10 pfu	71.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4307	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human hepatoma	Li-7	4000 cells per well	NA	MTT assay	10 pfu	72.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4308	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate adenocarcinoma	PC-3	4000 cells per well	NA	MTT assay	10 pfu	72.7 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4309	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human gastric carcinoma	NCI-N87	4000 cells per well	NA	MTT assay	10 pfu	76.4 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4310	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human nasopharyngeal carcinoma	HNE-1	4000 cells per well	NA	MTT assay	10 pfu	76.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4311	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human gastric carcinoma	HGC-27	4000 cells per well	NA	MTT assay	10 pfu	79.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4312	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human hepatoma	PLC	4000 cells per well	NA	MTT assay	10 pfu	80.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4313	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human colorectal carcinoma	HCT-116	4000 cells per well	NA	MTT assay	10 pfu	81.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4314	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	DBTRG-05MG	4000 cells per well	NA	MTT assay	10 pfu	83.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4315	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas adenocarcinoma	Capan-1	4000 cells per well	NA	MTT assay	10 pfu	85.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4316	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human acute promyelocytic leukemia	HL-60	4000 cells per well	NA	MTT assay	10 pfu	85.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4317	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human mammary ductal carcinoma	T-47D	4000 cells per well	NA	MTT assay	10 pfu	86.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4318	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human nonsmall cell lung cancer	NCI-H358	4000 cells per well	NA	MTT assay	10 pfu	87.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4319	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma	HepG2	4000 cells per well	NA	MTT assay	10 pfu	88.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4320	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human breast adenocarcinoma	SK-BR-3	4000 cells per well	NA	MTT assay	10 pfu	89.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4321	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate carcinoma	Du145	4000 cells per well	NA	MTT assay	10 pfu	91.4 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4322	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human gastric adenocarcinoma	AGS	4000 cells per well	NA	MTT assay	10 pfu	92.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4323	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	LN-18	4000 cells per well	NA	MTT assay	10 pfu	92.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4324	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human breast adenocarcinoma	MCF-7	4000 cells per well	NA	MTT assay	10 pfu	95.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4325	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human bladder transitional cell carcinoma	EJ	4000 cells per well	NA	MTT assay	10 pfu	95.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4326	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human nonsmall cell lung cancer	H-1299	4000 cells per well	NA	MTT assay	10 pfu	96.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4327	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder transitional cell carcinoma	J82	4000 cells per well	NA	MTT assay	10 pfu	96.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4328	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	LN-229	4000 cells per well	NA	MTT assay	10 pfu	98.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4329	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	A-172	4000 cells per well	NA	MTT assay	10 pfu	98.7 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4330	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas adenocarcinoma	BxPC-3	4000 cells per well	NA	MTT assay	10 pfu	98.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4331	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human large cell lung cancer	NCI-H460	4000 cells per well	NA	MTT assay	10 pfu	99.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4332	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human cervix squamous cell carcinoma	SiHa	4000 cells per well	NA	MTT assay	10 pfu	99.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4333	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	0.001 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4334	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	0.01 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4335	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	0.1 MOI	50% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4336	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	10 MOI	38% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347