| Primary information |
|---|
| OV_ID | OV_585 |
| Virus Name | Alphavirus |
| Strain | M1 |
| Virus type | RNA |
| Virus family | Togaviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human pancreatic ductal adenocarcinoma cell line |
| Cell line | Capan-1 |
| Concentration of cell line | 4000 |
| In-vitro toxicity | Non toxic to human immortalized liver cell line L-02 |
| Assay | MTT assay |
| In-vitro virus concentration | 0.01 PFU/cell |
| In-vitro result | 100% cancer cell viability at 72 hours post-infection |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | M1 upregulated transcriptional ISGs (329 shown here) |
| Clinical trial | NA |
| PMID | 27374176 |