Detailed description page of Selected OV_ID


OV_589 details
Primary information
OV_IDOV_589
Virus Name Alphavirus
StrainM1
Virus typeRNA
Virus familyTogaviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic ductal adenocarcinoma cell line
Cell lineCapan-1
Concentration of cell line4000
In-vitro toxicityNon toxic to human immortalized liver cell line L-02
AssayMTT assay
In-vitro virus concentration1 PFU/cell
In-vitro result90% cancer cell viability at 72 hours post-infection
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectM1 upregulated transcriptional ISGs (329 shown here)
Clinical trialNA
PMID27374176