The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_618	Adenovirus	CRAd-CCL21-IL15	DNA	Adenoviridae	Insertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells	Yes	No	IL-15	NA	NA	NA	NA	NA	NA	NA	NA	SCID mice were injected intradermally 4.0E+6 Caco-2 cells	4.0E+8 IFU	NA	Reduction in tumor volume to 550 cubic millimeter compared to control 3100 cubic millimeter after 40 days	Intratumoral	NA	NA	NA	27380620
OV_729	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	10 MOI	97% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_730	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	10 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_731	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	52% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_732	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	50% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_733	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	33% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_734	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	38% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_735	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_736	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_737	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	50 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_738	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	50 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_739	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_740	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_741	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	80% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_742	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	50% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_743	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	65% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_744	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	45% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_745	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	61% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_746	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	61% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_747	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	46% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_748	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	46% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_749	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	HepG2 orthotopic liver xenograft tumor in Balb/c athymic nude	NA	NA	Reduction in tumor weight to 0.2 g compared to control 0.75 g after 18 days	intravenously	NA	NA	NA	27450327
OV_750	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	HepG2 orthotopic liver xenograft tumor in Balb/c athymic nude	NA	NA	Reduction in tumor weight to 0.2 g compared to control 0.75 g after 18 days	intravenously	NA	NA	NA	27450327
OV_751	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	HepG2 orthotopic liver xenograft tumor in Balb/c athymic nude	NA	NA	Reduction in tumor weight to 0.85 g compared to control 0.75 g after 18 days	intravenously	NA	NA	NA	27450327
OV_752	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	HepG2 subcutaneous liver xenograft tumor in Balb/c athymic nude	NA	NA	Reduction in tumor volume to 0.8 cubic centimeter compared to control 2.4 cubic centimeter after 15 days	intravenously	NA	NA	NA	27450327
OV_753	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	90% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_754	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	58% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_755	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	41% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_756	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	36% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_757	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	25% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_758	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_759	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	60% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_760	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	49% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_761	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	36% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_762	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	30% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_763	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	99% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_764	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	76% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_765	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	64% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_766	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	60% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_767	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	52% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_768	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_769	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	60% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_770	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_771	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	46% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_772	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	40% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_773	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_774	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	65% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_775	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	55% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_776	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	46% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_777	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	39% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_778	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	88% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_779	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	60% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_780	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	50% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_781	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	39% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_782	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	38% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_783	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	90% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_784	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	57% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_785	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	30% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_786	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	11% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_787	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	9% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_788	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_789	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	45% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_790	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	34% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_791	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	11% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_792	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	8% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_793	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	99% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_794	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	60% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_795	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	49% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_796	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	35% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_797	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	30% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_798	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_799	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	40% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_800	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	32% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_801	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	25% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_802	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	20% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_803	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_804	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	56% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_805	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	34% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_806	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	21% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_807	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	18% cancer cell viability at 120 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_808	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	90% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_809	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	50% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_810	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	39% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_811	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	21% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_812	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	BV-173	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	18% cancer cell viability at 96 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_813	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 40 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_814	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	42% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_815	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 40 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	64% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_816	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_817	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_818	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 240 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	76% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_819	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	64% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_820	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 240 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	55% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_821	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 40 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	35% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_822	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human chronic myelogenous leukemic cell line	K562	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	29% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_823	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 40 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_824	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute lymphoblastic leukemic cell line	SUP-B15	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	38% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_825	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	40% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_826	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 240 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human megakaryoblastic leukemic cell line	MEG-01	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	39% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_827	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	No	Viral strain in combination with DNR 120 ng/ml	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	NB4	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927