Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2628	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	100 MOI	5% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2629	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	100 MOI	15% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2630	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SGC7901 (1.0E+6 cells)	1.0E+9 pfu	NA	Complete regression in tumor after 9 weeks and increase in median survival time upto 55 days	Intratumoral	Induction of apoptosis in cancer	NA	NA	22842823
OV_2631	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SGC7901 (1.0E+6 cells)	1.0E+9 pfu	NA	Significant reduction in tumor volume and increase in median survival time ipto 345 days	Intravenous	Induction of apoptosis in cancer	NA	NA	22842823
OV_2632	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	Yes	No	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	80% cell survival after 3 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2633	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	Yes	No	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	60% cell survival after 6 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2634	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	Yes	No	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	90% cell survival after 3 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2635	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	Yes	No	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	60% cell survival after 6 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2636	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	70% cell survival after 3 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2637	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	30% cell survival after 6 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2638	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	60% cell survival after 3 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2639	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell survival after 6 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2640	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	60% cell survival after 3 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2641	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	30% cell survival after 6 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2642	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	60% cell survival after 3 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2643	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell survival after 6 days	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2644	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	0.001 MOI	80% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2645	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	80% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2646	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	60% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2647	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	50% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2648	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2649	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	0.001 MOI	80% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2650	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	70% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2651	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	40% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2652	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2653	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	1.0E+4 cells per well	NA	MTT assay	10 MOI	10% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2654	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	0.001 MOI	80% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2655	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	80% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2656	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	60% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2657	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	50% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2658	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug Bvdu (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	10 MOI	30% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2659	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	0.001 MOI	70% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2660	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	70% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2661	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	30% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2662	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2663	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MCF-7	1.0E+4 cells per well	NA	MTT assay	10 MOI	10% cell survival	No	No	NA	No response	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2664	Adenovirus	SG500-dNK	DNA	Adenoviridae	Addition of deoxyribonucleoside kinase	No	Virus in combination with drug dFdC (1 micromolar)	No	Shanghai cell collection	Human breast cancer cell line	MDA-MB-231	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for MDA-MB-231(5.0E+6 cells)	1.0E+9 pfu	NA	Increase in median survival time to more than 100 days compared to control and reduction in tumor volume 663.85 +/- 379.39mm compared to control 1336.46 +/- 614.81	NA	Combination of drug and virus increase the apoptosis process	NA	NA	23000515
OV_2690	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	85% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2691	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2692	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2693	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	50% cell viability after 96 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2694	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2695	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2696	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2697	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 96 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2698	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	85% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2699	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2700	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2701	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 96 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2702	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	70% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2703	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2704	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	20% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2705	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2706	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2707	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	10% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2708	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus strain in combination with CIK (1 Ã— 10â· )	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	SCID mice xenograft for Huh7 (1.0E+6 cell)	2.0E+8 pfu	NA	Reduction in tumor volume below 100mm after 40 days and increase in median survival time 40 days	Intratumoral	NA	NA	NA	23028626
OV_2709	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus strain in combination with CIK (1 Ã— 10â· )	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	SCID mice xenograft for Huh7 (1.0E+6 cell)	2.0E+8 pfu	NA	Reduction in tumor volume below 100mm after 40 days and increase in median survival time 40 days	Intravenous	NA	NA	NA	23028626
OV_2710	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	Yes	No	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	5 MOI	90% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2711	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	Yes	No	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	10 MOI	85% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2712	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	Yes	No	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	20 MOI	85% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2713	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	Yes	No	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	50 MOI	80% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2714	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	Yes	No	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	100 MOI	70% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2715	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	Yes	No	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	200 MOI	60% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2716	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (0.1 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	5 MOI	90% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2717	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (1 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	5 MOI	70% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2718	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (5 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	5 MOI	60% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2719	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (10 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	5 MOI	50% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2720	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	5 MOI	40% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2721	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	10 MOI	90% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2722	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	10 MOI	70% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2723	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	10 MOI	50% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2724	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	10 MOI	50% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2725	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	10 MOI	40% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2726	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	20 MOI	90% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2727	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	20 MOI	70% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2728	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	20 MOI	50% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2729	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	20 MOI	50% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2730	Adenovirus	SG600	DNA	Adenoviridae	Deletion of E1A, E1B promoter and E1ACR2 region	No	Virus strain in combination with vincristine (50 nm)	No	Central south university,China	Human retinoblastoma cell line	HXO-RB44	NA	NA	cell proliferation kit analysis	20 MOI	40% cell survival	No	No	NA	No response	NA	S-phase arrest and induction of apotosis	Downregulation of Akt pathway	NA	23109819
OV_2731	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2732	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2733	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2734	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	50% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2735	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2736	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2737	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	50% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2738	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	30% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2739	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2740	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2741	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	82% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2742	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	78% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2743	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2744	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2745	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2746	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	MTT assay	5 MOI	40% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2747	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2748	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	5 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2749	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	5 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2750	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	5 MOI	40% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2751	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2752	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	5 MOI	50% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172

previous 1 2...8 9 101112 13 14...17 18 next