Primary information |
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OV_ID | OV_2657 |
Virus Name | Adenovirus |
Strain | SG500-dNK |
Virus type | DNA |
Virus family | Adenoviridae |
Modification in virus genome | Addition of deoxyribonucleoside kinase |
Virus alone | No |
Virus in combination iwth drug/radiation | Virus in combination with drug Bvdu (1 micromolar) |
Immune gene induction in virus genome | No |
Source of cell line | Shanghai cell collection |
Origin of cell line | Human breast cancer cell line |
Cell line | MCF-7 |
Concentration of cell line | 1 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 1 MOI |
In-vitro result | 50% cell survival |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Combination of drug and virus increase the apoptosis process |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 23000515 |