| Primary information |
|---|
| OV_ID | OV_2732 |
| Virus Name | Adenovirus |
| Strain | AdCN205 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | Virus expressing IL-24 gene |
| Source of cell line | ATCC |
| Origin of cell line | Human hepatocellular carcinoma cell line |
| Cell line | PLC5 |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 5 MOI |
| In-vitro result | 90% cell viability after 48 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Induction of apoptosis, G1 arrest and sensescence |
| Immunogenic effect | Inhibition of oncogene and antiapototic gene |
| Clinical trial | NA |
| PMID | 23292172 |