Detailed description page of Selected OV_ID


OV_2745 details
Primary information
OV_IDOV_2745
Virus Name Adenovirus
StrainAdCN205
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with miR-34-a
Immune gene induction in virus genomeVirus expressing IL-24 gene
Source of cell lineATCC
Origin of cell lineHuman hepatocellular carcinoma cell line
Cell lineBEL-7404
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration5 MOI
In-vitro result60% cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis, G1 arrest and sensescence
Immunogenic effectInhibition of oncogene and antiapototic gene
Clinical trialNA
PMID23292172