Detailed description page of Selected OV_ID


OV_2726 details
Primary information
OV_IDOV_2726
Virus Name Adenovirus
StrainSG600
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1A, E1B promoter and E1ACR2 region
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with vincristine (50 nm)
Immune gene induction in virus genomeNo
Source of cell lineCentral south university,China
Origin of cell lineHuman retionoblastoma cell line
Cell lineHXO-RB44
Concentration of cell line0
In-vitro toxicityNA
Assaycell proliferation kit analysis
In-vitro virus concentration20 MOI
In-vitro result90% cell survival
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionS-phase arrest and induction of apotosis
Immunogenic effectDownregulation of Akt pathway
Clinical trialNA
PMID23109819