| Primary information |
|---|
| OV_ID | OV_2711 |
| Virus Name | Adenovirus |
| Strain | SG600 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | Deletion of E1A, E1B promoter and E1ACR2 region |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | Central south university,China |
| Origin of cell line | Human retionoblastoma cell line |
| Cell line | HXO-RB44 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | cell proliferation kit analysis |
| In-vitro virus concentration | 10 MOI |
| In-vitro result | 85% cell survival |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | S-phase arrest and induction of apotosis |
| Immunogenic effect | Downregulation of Akt pathway |
| Clinical trial | NA |
| PMID | 23109819 |