The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2528	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	0.1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2529	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2530	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	35% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2531	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	0.1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2532	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2533	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	60% cellsa are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2534	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2535	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2536	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	30% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2537	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	90% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2538	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2539	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	70% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2540	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	60% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2541	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	90% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2542	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2543	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	70% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2544	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	60% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2545	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	100% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2546	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2547	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	40% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2548	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	10% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2549	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	90% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2550	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	70% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2551	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	50% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2552	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	30% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2553	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for Huh7 cell line (1.0E+7)	3.0E+8 pfu	NA	Reduction in tumor volume below 425mm after 16 days	Intratumoral	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2554	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	90.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2555	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	70.3% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2556	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	56.2% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2557	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	25.3% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2558	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	88.3% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2559	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	64% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2560	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	35.2% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2561	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	17.7% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2562	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	88.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2563	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	72.3% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2564	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	58% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2565	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	28% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2566	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	84.3% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2567	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	66.2% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2568	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	54.5% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2569	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	24% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2570	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2571	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	72.5% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2572	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	50.2% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2573	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	28.2% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2574	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	87.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2575	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	68% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2576	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	45% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2577	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	25% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2578	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for HCCLM3 cell line	2.0E+8 pfu	NA	Significant reduction in tumor volume from the onset of tretament and till the end of 42 days and increase in median survival time	Intratumoral	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2579	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22640485
OV_2580	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	1.0E+5 cells per well	NA	MTT assay	1 MOI	100% cell survival	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22640485
OV_2581	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	1.0E+5 cells per well	NA	MTT assay	10 MOI	50% cell survival	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22640485
OV_2582	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	1.0E+5 cells per well	NA	MTT assay	100 MOI	20% cell survival	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22640485
OV_2583	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	1.0E+5 cells per well	NA	MTT assay	1000 MOI	10% cell survival	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22640485
OV_2584	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	1.0E+5 cells per well	NA	MTT assay	10000 MOI	All cells are dead	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22640485
OV_2585	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	NA	NA	NA	NA	NA	Nu/Nu female mice orthotopic for MDA-MB-231 cell line (8.0E+7 cells)	1.0E+8 pfu	NA	Tumor volume comes to 1000mm as compared to normal 2000 after 42 days	Intratumoral	Induction of apoptosis in cancer	NA	NA	22640485
OV_2586	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	NA	NA	NA	NA	NA	Nu/Nu female mice orthotopic for MDA-MB-231 cell line (8.0E+7 cells)	2.0E+8 pfu	NA	Tumor volume comes to below 1000mm as compared to normal 2000 after 42 days	Intratumoral	Induction of apoptosis in cancer	NA	NA	22640485
OV_2587	Adenovirus	CNHK600-IL24	DNA	Adenoviridae	Deletion of E1B gene and addition of IL-24 gene	Yes	No	Virus expressing IL-24 gene	Shanghai laboratory animal center, China	Human breast cancer cell line	MDA-MB-231	NA	NA	NA	NA	NA	Nu/Nu female mice orthotopic for MDA-MB-231 cell line (8.0E+7 cells)	4.0E+8 pfu	NA	Tumor volume comes to 500mm as compared to normal 2000 after 42 days	Intratumoral	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22640485
OV_2588	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	HepG2	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2589	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Huh-7	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2590	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	SMMC7721	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2591	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2592	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Hep3B	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2593	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Hep3B	5.0E+4 cells per well	NA	Crystal violet staining	0.1 MOI	100% cells viavility	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2594	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Hep3B	5.0E+4 cells per well	NA	Crystal violet staining	1 MOI	Some cells are viable	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2595	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Hep3B	5.0E+4 cells per well	NA	Crystal violet staining	10 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2596	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Hep3B	5.0E+4 cells per well	NA	Crystal violet staining	100 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2597	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	0.1 MOI	100% cells viavility	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2598	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	1 MOI	Some cells are viable	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2599	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	10 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2600	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	100 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2601	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Huh-7	5.0E+4 cells per well	NA	Crystal violet staining	0.1 MOI	100% cells viavility	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2602	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Huh-7	5.0E+4 cells per well	NA	Crystal violet staining	1 MOI	Some cells are viable	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2603	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Huh-7	5.0E+4 cells per well	NA	Crystal violet staining	10 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2604	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Huh-7	5.0E+4 cells per well	NA	Crystal violet staining	100 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2605	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	Huh-7	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for Huh7 cell line (5.0E+6 cells)	4.0E+8 pfu	NA	Complete regression in tumor after 28 days	Intratumoral	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2606	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	5% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2607	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	10% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2608	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2609	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	30% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2610	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2611	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	50% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2612	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	60% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2613	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	70% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2614	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	50% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2615	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	70% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2616	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2617	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2618	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	1 MOI	No cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2619	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	1 MOI	10% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2620	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	1 MOI	10% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2621	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2622	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	10 MOI	10% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2623	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	10 MOI	10% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2624	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	10 MOI	No cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2625	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	10 MOI	15% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2626	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	100 MOI	20% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2627	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	GES-1	1.0E+4 cells per well	NA	MTT assay	100 MOI	20% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823