Detailed description page of Selected OV_ID


OV_2581 details
Primary information
OV_IDOV_2581
Virus Name Adenovirus
StrainCNHK600-IL24
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1B gene and addition of IL-24 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing IL-24 gene
Source of cell lineShanghai laboratory animal center, China
Origin of cell lineHuman breast cancer cell line
Cell lineMDA-MB-231
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result50% cell survival
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis in cancer
Immunogenic effectNA
Clinical trialNA
PMID22640485