Detailed description page of Selected OV_ID


OV_2542 details
Primary information
OV_IDOV_2542
Virus Name Adenovirus
StrainAD55-Apoptin
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1B gene and insertion of Apoptin gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman hepatocellular carcinoma cell line
Cell lineHep3B
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result80% cells viable after day 2
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apotosis as measured by TUNEL assay
Immunogenic effectNA
Clinical trialNA
PMID22321574