Detailed description page of Selected OV_ID


OV_2621 details
Primary information
OV_IDOV_2621
Virus Name Adenovirus
StrainAd-hTERT-E1a-Apoptin
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of E1a and apoptin before hTERT promoter
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineType culture collection of chines academy, shanghai
Origin of cell lineHuman gastric cancer cell line
Cell lineGES-1
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro result20% cell growth suppression after day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis in cancer
Immunogenic effectNA
Clinical trialNA
PMID22842823