The total number record retrieved from this search are 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	59% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_2	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	56% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_3	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	49% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_4	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	90% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_5	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_6	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_7	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_8	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	60% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_9	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_10	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	10 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_11	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	50 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_12	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	100 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_13	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	10 MOI	100% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_14	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	50 MOI	95% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_15	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	100 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_16	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	10 MOI	77% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_17	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	50 MOI	72% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_18	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	100 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_19	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_20	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_21	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_22	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	100% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_23	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	95% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_24	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_25	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	77% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_26	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	72% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_27	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_28	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	80% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_29	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_30	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	40% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_31	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	90% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_32	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	82% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_33	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	84% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_34	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	89% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_35	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_36	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_40	Adenovirus	AdCMV/GFP	DNA	Adenoviridae	Mutant with E1 deletion carrying a green fluorescent protein (GFP)	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Highly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	13% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_41	Adenovirus	Ad dl1520	DNA	Adenoviridae	E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	54% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_42	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	18% cancer cell viability	No	No	NA	No response	NA	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304
OV_43	Adenovirus	AdCMV/GFP	DNA	Adenoviridae	Mutant with E1 deletion carrying a green fluorescent protein (GFP)	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Highly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	22% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_44	Adenovirus	Ad dl1520	DNA	Adenoviridae	E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	55% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_45	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	55% cancer cell viability	No	No	NA	No response	NA	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304
OV_47	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	57% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_48	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with etoposide (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.67 CDI	MTT assay	0.1 MOI	24% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_49	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with epirubicin (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.46 CDI	MTT assay	0.1 MOI	16% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_50	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with doxorubicin (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.88 CDI	MTT assay	0.1 MOI	26% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_51	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with vincristine (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.79 CDI	MTT assay	0.1 MOI	25% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_52	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with colchcine (0.02 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.81 CDI	MTT assay	0.1 MOI	28% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_53	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	18% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_54	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with etoposide (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.27 CDI	MTT assay	0.1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_55	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with epirubicin (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.31 CDI	MTT assay	0.1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_56	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with doxorubicin (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.33 CDI	MTT assay	0.1 MOI	6% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_57	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with vincristine (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.89 CDI	MTT assay	0.1 MOI	12% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_58	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with colchcine (0.02 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.78 CDI	MTT assay	0.1 MOI	10% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_268	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	20 MOI	92% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_269	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	50 MOI	95% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_270	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	100 MOI	92% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_271	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_272	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	200 MOI	88% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_273	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	92% cancer cell viability at 24 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_274	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	85% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_275	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	90% cancer cell viability at 96 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_276	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	50 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_277	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	100 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_278	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	85% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_279	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	83% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_280	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	92% cancer cell viability at 24 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_281	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	94% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_282	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	86% cancer cell viability at 96 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_283	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	20 MOI	88% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_284	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	50 MOI	75% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_285	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	100 MOI	77% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_286	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	74% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_287	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	200 MOI	70% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_288	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	90% cancer cell viability at 24 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_289	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	83% cancer cell viability at 48 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_290	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	71% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_291	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	50 MOI	91% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_292	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	100 MOI	85% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_293	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	65% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_294	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	56% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_295	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	92% cancer cell viability at 24 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_296	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	81% cancer cell viability at 48 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_297	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	61% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_298	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	50 MOI	78% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_299	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	No	Virus combined with recombinant human CD47 Fc chimera (rhCD47-Fc) - 1μg/mL	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	50 MOI	82% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_300	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	No	Virus combined with recombinant human CD47 Fc chimera (rhCD47-Fc) - 5μg/mL	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	50 MOI	96% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_301	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	100% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_302	Adenovirus	Ad.IL3	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-IL3 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	90% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_303	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	80% cancer cell viability at 48 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_304	Adenovirus	Ad.IL3	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-IL3 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	100% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_305	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	20 MOI	92% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_306	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	50 MOI	65% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_307	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	100 MOI	58% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_308	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	150 MOI	52% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_309	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	K562	2.0E+4 cells per well	NA	MTT assay	200 MOI	44% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_310	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	50 MOI	82% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_311	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	100 MOI	58% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_312	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	52% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_313	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	38% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307