Detailed description page of Selected OV_ID


OV_275 details
Primary information
OV_IDOV_275
Virus Name Adenovirus
StrainAd.sp-E1A
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeViral E1A promoter was replaced by human survivin promoter (hsurP)
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineLeukemia cell line
Cell lineK562
Concentration of cell line2
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration150 MOI
In-vitro result90% cancer cell viability at 96 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26554307