| 1075 | CKS-17 | LQNRRGLDLLFLKEGGL | 17 | L | None | Conjugated to HSA (human serum albumin) | None | Linear | Synthetic | Homologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirus | Lymphocyte | Inhibits the Proliferation of Purified Lymphocytes | In vitro | Mononuclear Cells, Lymphocytes, Human Neutrophils, Lymphoblastoid cell line-Jurkat cell, | 10 micromolar in Lymphocyte proliferation assays | None | Lymphocyte Proliferation assay | NA | NA | 1921761 | 1991 |
| 1076 | CKS-17 | LQNRRGLDLLFLKEGGL | 17 | L | None | Conjugated to HSA (human serum albumin) | None | Linear | Synthetic | Homologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirus | Protein Kinase C | Inhibits Protein Kinase C activity | In vitro | Human Neutrophils, Lymphoblastoid cell line-Jurkat cell | 3 micromolar in the in vitro protein kinase C assay | None | Protein kinase assay | NA | NA | 1921761 | 1991 |
| 1077 | CKS-17 | LQNRRGLDLLFLKEGGL | 17 | L | None | Conjugated to BSA (bovine serum albumin) | None | Linear | Synthetic | Homologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirus | Protein Kinase C | inhibition of IL-1-mediated responses, due to inactivation of PKC. inactivates PKC directly without competing with its cofactors. | In vitro | Human Neutrophils, Lymphoblastoid cell line-Jurkat cell | 3 micromolar in the in vitro protein kinase C assay | None | Protein kinase assay | NA | NA | 1921761 | 1991 |
| 1078 | CSK-17 | LQNRRGLDLLFLKEGGL | 18 | L | None | None | None | Linear | Synthetic | NA | NA | Inhibition of human Lymphocyte | NA | NA | NA | NA | NA | NA | NA | 2421920 | 1986 |
| 1088 | ISU-peptide | LQARILAVERYLKDQQL | 17 | L | None | None | None | Linear | Protein Derived | HIV-1 isolate HXB2 | IL-2 | HIV env 583-599 conjugated to a carrier protein to inhibit the cytopathic effect of HIV-1. This inhibition of vims replication may be due to blocking of a secondary receptor, to inhibition of target cell proliferation preventing virus replication or to both effects | Both | Murine CTL-6, human T-cell lines MT4, Molt4/clone 8 | NA | Balb/c mice | Lymphocyte Proliferation assays, cytopathogenicity assay | NA | NA | 7986401 | 1994 |
| 1095 | HLA-A2 (98-113) | HRVDLGTLRGYYNQSE | 16 | L | None | None | None | Linear | Protein Derived | MHC molecule | NA | NA | Both | NA | NA | LEW rat | Graft transplation assay | NA | NA | 8573307 | 1995 |
| 1099 | gp41 portion of gp160 peptide | LSVWGIRQLRARLLALE | 17 | L | None | None | None | Linear | Protein Derived | GP160 protein of HIV | NA | Induced progressive inhibition of PHA-induced lymphocyte proliferation | Both | CTLL-2, murine IL-2-dependent cell line | NA | Balb/c mice, 4-12 months old | Proliferation assay | NA | Interferon α, PGE 2 | 8582788 | 1995 |
| 1101 | Recombinant Soluble HIV-2 GP36 (565-581) | LRLTVWGTKNLQARVTA | 17 | L | None | None | None | Linear | Protein Derived | HIV-2 (derived from clone ROD) | Con A | Inhibits Con A and protein kinase C (PKC) activity | In vitro | Human H9, Jurkat, Raji, Daudi. U937 and HEF cell lines | NA | NA | BrdU-Labeling and Detection-Kit | NA | NA | 8847089 | 1995 |
| 1102 | ISP-GP41 (583-599) | VERYLKDQQLLGIWGCS | 17 | L | None | None | None | Linear | Protein Derived | HIV-l (derived from clone BH10) | Con A | Inhibits protein kinase C (PKC) activity | In vitro | Human H9, Jurkat, Raji, Daudi. U937 and HEF cell lines | NA | NA | BrdU-Labeling and Detection-Kit | NA | NA | 8847089 | 1995 |
| 1103 | HIV-1 gp41 (conjugated with BSA) | LQARILAVERYLKDQQL | 17 | L | None | None | None | Linear | Protein Derived | HIV-1 isolate IIIB | NA | Mimics the effect of human IFN-α and -β on regulation of human MHC class I expression | In vitro | Human H9, Jurkat, Raji, Daudi. U937 and HEF cell lines | NA | NA | NA | NA | NA | 9373217 | 1997 |
| 1110 | H17 | LQNRRGLDLLTAEKGGL | 17 | L | None | Amidation | None | Linear | Protein Derived | Human endogenous retroviruses HERV-H/env60 (HERV-H) | NA | Induces CCL19 production in tumor cells, promotion of both CD271+ cell-governing immunosuppression and tumor invasion via the Twist-PI3K pathway. | Both | Colon cancer Colo320 and HCT116,pancreatic cancer MIAPaca and Panc1,melanoma Hs294T, andnormal epithelial cell ARPE19 | NA | Female BALB/c nu/nu mice | WST1 assay | NA | NA | 24590808 | 2014 |
| 1130 | CKS-17 | LQNRRGLDLLFLKEGGLC | 18 | L | None | None | None | Linear | Protein Derived | murine leukemia virus (MLV) | TNF-α | Significantly reduces the mRNA levels of IL-17C, TNF-α, IL-6 and CXCL2 | Both | Acute allergic contact dermatitis model and TPA toxic eczema model | NA | C57BL/6 mice and BALB/CJ mice | NA | NA | NA | 24245569 | 2013 |
| 1140 | CKS-17 | LQNRRGLDLLFLKEGGL | 17 | L | None | None | None | Linear | Synthetic | NA | Protein kinase | Activates mitogen-activated protein (MAP) kinases extracellular signal-regulated kinase 1 and 2 (ERK1/2) | In vitro | Human monocytic cell line THP-1 | NA | NA | NA | NA | NA | 11359835 | 2001 |
| 1159 | RDP1258 | RnlnlnLRnlnLnLGY | 16 | Mix | None | None | None | Linear | Natural | HLA/MHC molecule | NA | Not Available | Both | In silico screening (MD simulations) | 1.2±0.2 micromolar | CBA and C57BI/6 mice | Graft transplation assay | NA | NA | 9702773 | 1998 |
| 1161 | HIV-env 579-595 | GIKQLQARILAVERYLK | 17 | L | None | None | None | Linear | Synthetic | NA | NA | Not Available | In vitro | Human sera | NA | NA | NA | NA | NA | 2455899 | 1988 |
| 1162 | HIV-env 583-599 (pHIVIS) | LQARILAVERYLKDQQL | 17 | L | None | None | None | Linear | Synthetic | NA | NA | Not Available | In vitro | Human sera | NA | NA | NA | NA | NA | 2455899 | 1988 |
| 1163 | HIV-env:inv 599-583 | LQQDKLYREVALIRAQL | 17 | L | None | None | None | Linear | Synthetic | NA | NA | Not Available | In vitro | Human sera | NA | NA | NA | NA | NA | 2455899 | 1988 |
| 1165 | HIV-env 587-603 | ILAVERYLKDQQLLGIW | 17 | L | None | None | None | Linear | Synthetic | NA | NA | Not Available | In vitro | Human sera | NA | NA | NA | NA | NA | 2455899 | 1988 |
| 1167 | HIV-env 848-863 | RHIPRRIRQGLERILL | 16 | L | None | None | None | Linear | Synthetic | NA | NA | Not Available | In vitro | Human sera | NA | NA | NA | NA | NA | 2455899 | 1988 |
| 1169 | CS-1 (HTLV-1) | AQNRRGLDLLFWEQGGL | 17 | L | None | None | None | Linear | Synthetic | HTLV-I gp21E | NA | Not Available | In vitro | CTL-2 | 3 nmol/well | NA | NA | NA | NA | 2973436 | 1988 |
| 1170 | CS-3 (HIV) | LQARILAVERYLKDQQL | 17 | L | None | None | None | Linear | Synthetic | HIV gp41 | NA | Not Available | In vitro | CTL-2 | 3 nmol/well | NA | NA | NA | NA | 2973436 | 1988 |
| 1171 | CS-2 (Endogenous) | YQNRLALDYLLAAEGGV | 17 | L | None | None | None | Linear | Synthetic | Human genomic DNA | NA | Not Available | In vitro | CTL-2 | NA | NA | NA | NA | NA | 2973436 | 1988 |
| 1180 | Immunosuppressive epitope of retroviral plSE | not available | 17 | L | None | None | None | Linear | Protein Derived | Retroviral protein pl5E | IL-2, TNF-α, protein kinase-C | Inhibits human mitogen and alloantigen-stimulated lymphocyte proliferation, natural killer cell activity, interleukin 1-mediated monocyte tumor killing, interleukin 2 production, immunoglobulin synthesis, TNF-α mRNA expression and protein kinase C activity | Both | U937, P2, JLS-V5 | NA | BALB/c mice (Female, 12- week-old) | NA | NA | NA | 7511054 | 1994 |
| 1181 | CKS-17 | LONRRGLDLLFLKEGGL | 17 | L | None | None | None | Linear | Synthetic | Not available | NA | Not Available | In vitro | U937, P2, JLS-V5 | NA | NA | NA | NA | NA | 7511054 | 1994 |
| 1192 | CKS-17 | LQNRRGLDLLFLKEGGL | 17 | L | None | None | None | Linear | Synthetic | NA | NA | Not Available | In vitro | Human Lymphoblastoid Cell Line | NA | NA | NA | NA | NA | 3201749 | 1988 |
| 1193 | SEQ ID NO:1 | ILNRKAIDFLLQRWGGT | 17 | L | None | None | polyethylene glycol conjugated | Linear | Protein Derived | Zaire ebola virus, C-terminus domain of the envelope glycoprotein | CD4+, CD8+ cells | Depletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 level | In vitro | PBMC | NA | NA | NA | NA | polyethylene glycol conjugated | US 20070185025 A1 | 2007 |
| 1194 | SEQ ID NO:2 | LINRHAIDFLLTRWGGT | 17 | L | None | None | polyethylene glycol conjugated | Linear | Protein Derived | Lake Victoria marburg virus | CD4+, CD8+ cells | Depletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 level | In vitro | PBMC | NA | NA | NA | NA | polyethylene glycol conjugated | US 20070185025 A1 | 2007 |
| 1195 | SEQ ID NO:3 | ILNRKAIDFLLRRWGGT | 17 | L | None | None | polyethylene glycol conjugated | Linear | Protein Derived | Sudan ebola virus,C-terminus domain of the envelope glycoprotein | CD4+, CD8+ cells | Depletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 level | In vitro | PBMC | NA | NA | NA | NA | polyethylene glycol conjugated | US 20070185025 A1 | 2007 |
| 1196 | SEQ ID NO:4 | LLNRKAIDFLLQRWGGT | 17 | L | None | None | polyethylene glycol conjugated | Linear | Protein Derived | Reston ebola virus, C-terminus domain of the envelope glycoprotein | CD4+, CD8+ cells | Depletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 level | In vitro | PBMC | NA | NA | NA | NA | polyethylene glycol conjugated | US 20070185025 A1 | 2007 |
| 1197 | SEQ ID NO:5 | ILNRKAIDFLLQRWGGT | 17 | L | None | None | polyethylene glycol conjugated | Linear | Protein Derived | Ivory coast ebola virus, C-terminus domain of the envelope glycoprotein | CD4+, CD8+ cells | Depletion and inactivation of T Lymphocytes, Modulating IL 2, IL10, IL12 level | In vitro | PBMC | NA | NA | NA | NA | polyethylene glycol conjugated | US 20070185025 A1 | 2007 |
| 1205 | NA | LQNRRGLDILFLQEGGLC | 18 | L | None | None | None | Linear | Synthetic | Retro virus, Feline leukemia virus (FLV) | NA | Inhibiting T-cell proliferation | In vitro | Spleen cells | NA | Murine (C57BL/6 strain) | Inhibition of Concanavalin A-induced T-cell Proliferation of murine | NA | NA | WO 1988005783 A1 | 1988 |
| 1208 | NA | QREKRAVGIGALFLGFLG | 18 | L | None | None | None | Linear | Synthetic | Retro virus | T-cells | Inhibiting T-cell proliferation | In vitro | Spleen cells | NA | Murine (C57BL/6 strain) | Inhibition of Concanavalin A-induced T-cell Proliferation of murine | NA | NA | WO 1988005783 A1 | 1988 |
| 1210 | NA | AQNRRGLDLLFWEQGGLC | 18 | L | None | None | None | Linear | Synthetic | Retro virus | T-cells | Inhibiting T-cell proliferation | In vitro | Spleen cells | NA | Murine (C57BL/6 strain) | Inhibition of Concanavalin A-induced T-cell Proliferation of murine | NA | NA | WO 1988005783 A1 | 1988 |
| 1220 | NA | CVRGLYIDFRKDLGWK | 16 | L | None | None | None | Linear | Synthetic | Retro virus | Lymphocytes, TGF | Inhibits cell proliferation, conjugated polypeptide block the binding of TGF-B to its receptor | Both | Mu-I-Lv | NA | DBA/IJ male mice | Thymidine incorporation assay, TGF-fi Radioreceptor Binding Assay, Mice arthritis model | NA | Coupled to carrier proteins or crosslinked to form polymers | CA2057896C | 2000 |
| 1243 | SEQ ID NO:l | YKLVCYYTSWSQYREG | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1244 | SEQ ID NO:2 | YTSWSQYREGDGSCFP | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1245 | SEQ ID NO:5 | LDRFLCTHIIYSFANI | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1246 | SEQ ID NO:6 | THIIYSFANISNDHID | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1247 | SEQ ID NO:12 | PNLKTLLSVGGWNFGS | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1248 | SEQ ID NO:16 | NTQSRRTFIKSVPPFL | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1249 | SEQ ID NO:17 | TFIKSVPPFLRTHGFD | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1250 | SEQ ID NO:18 | PPFLRTHGFDGLDLAW | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1251 | SEQ ID NO:19 | HGFDGLDLAWLYPGRR | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1252 | SEQ ID NO:20 | DLAWLYPGRRDKQHFT | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1253 | SEQ ID NO:28 | IDSSYDIAKISQHLD | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1254 | SEQ ID NO:29 | DIAKISQHLDFISIMT | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1255 | SEQ ID NO:30 | QHLDFISIMTYDFHGA | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1256 | SEQ ID NO:34 | SPLFRGQEDASPDRFS | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1257 | SEQ ID NO:37 | DYAVGYMLRLGAPASK | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
| 1258 | SEQ ID NO:38 | MLRLGAPASKLVMGIP | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
