Primary information |
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ID | 1130 |
Peptide Name | CKS-17 |
Sequence | LQNRRGLDLLFLKEGGLC |
Length | 18 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Protein Derived |
Source of Origin | murine leukemia virus (MLV) |
Target | TNF-α |
Mechanism of Action | Significantly reduces the mRNA levels of IL-17C, TNF-α, IL-6 and CXCL2 |
In vitro/In vivo | Both |
Cell Line | Acute allergic contact dermatitis model and TPA toxic eczema model |
Inhibition Concentartion | NA |
In vivo Model | C57BL/6 mice and BALB/CJ mice |
Assay | NA |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 24245569 |
Year of Publication | 2013 |
3-D Structure | View in Jmol or Download Structure |