Detailed description page of ImmunoSPdb

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1076 details
Primary information
ID1076
Peptide NameCKS-17
SequenceLQNRRGLDLLFLKEGGL
Length17
ChiralityL
N-terminal ModificationNone
C-terminal ModificationConjugated to HSA (human serum albumin)
Chemical ModificationNone
Linear/ CyclicLinear
NatureSynthetic
Source of OriginHomologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirus
TargetProtein Kinase C
Mechanism of ActionInhibits Protein Kinase C activity
In vitro/In vivoIn vitro
Cell LineHuman Neutrophils, Lymphoblastoid cell line-Jurkat cell
Inhibition Concentartion3 micromolar in the in vitro protein kinase C assay
In vivo ModelNone
AssayProtein kinase assay
Lethal DoseNA
Combination TherapyNA
Pubmed ID1921761
Year of Publication1991
3-D StructureNA