Primary information |
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ID | 1076 |
Peptide Name | CKS-17 |
Sequence | LQNRRGLDLLFLKEGGL |
Length | 17 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | Conjugated to HSA (human serum albumin) |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Synthetic |
Source of Origin | Homologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirus |
Target | Protein Kinase C |
Mechanism of Action | Inhibits Protein Kinase C activity |
In vitro/In vivo | In vitro |
Cell Line | Human Neutrophils, Lymphoblastoid cell line-Jurkat cell |
Inhibition Concentartion | 3 micromolar in the in vitro protein kinase C assay |
In vivo Model | None |
Assay | Protein kinase assay |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 1921761 |
Year of Publication | 1991 |
3-D Structure | NA |