Primary information |
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ID | 1075 |
Peptide Name | CKS-17 |
Sequence | LQNRRGLDLLFLKEGGL |
Length | 17 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | Conjugated to HSA (human serum albumin) |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Synthetic |
Source of Origin | Homologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirus |
Target | Lymphocyte |
Mechanism of Action | Inhibits the Proliferation of Purified Lymphocytes |
In vitro/In vivo | In vitro |
Cell Line | Mononuclear Cells, Lymphocytes, Human Neutrophils, Lymphoblastoid cell line-Jurkat cell, |
Inhibition Concentartion | 10 micromolar in Lymphocyte proliferation assays |
In vivo Model | None |
Assay | Lymphocyte Proliferation assay |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 1921761 |
Year of Publication | 1991 |
3-D Structure | NA |