1259 | SEQ ID NO:39 | PASKLVMGIPTFGRSF | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1260 | SEQ ID NO:46 | GTLAYYEICDFLRGAT | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1261 | SEQ ID NO:47 | EICDFLRGATVHRTLG | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1262 | SEQ ID NO:48 | RGATVHRTLGQQVPYA | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1263 | SEQ ID NO:53 | VKSKVQYLKDRQLAGA | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1264 | SEQ ID NO:54 | YLKDRQLAGAMVWALD | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1265 | SEQ ID NO:55 | LAGAMVWALDLDDFQG | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1266 | SEQ ID NO:56 | WALDLDDFQGSFCGQD | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1267 | SEQ ID NO:57 | DFQGSFCGQDLRFPLT | 16 | L | None | None | None | Linear | Protein Derived | Human Cartilage glycoprotein 39 | T-cells | Induce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intact | In vitro | PBMC | NA | NA | Peptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assay | NA | NA | WO 1997040068 A1 | 1997 |
1312 | CKS-17 | LQNRRGLDLLFLKEGGL | 17 | L | None | None | Coupled with carrier protein human serum albumin, bovine serum albumin | Linear | Protein Derived | Human T-cell Leukemia Virus envelope proteins | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T3 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1313 | CS-1 | AENRRGLDLLFWEQGGL | 17 | L | None | None | None | Linear | Protein Derived | Human T-cell Leukemia Virus envelope proteins | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T4 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1314 | CS-2 | YQNRLALDYLLAAEEGV | 17 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T5 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1315 | CS-3 | LEARILAVERYLKDQQL | 17 | L | None | None | None | Linear | Protein Derived | Human T-cell Leukemia Virus envelope proteins | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T6 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1316 | CS-SRV 17 | LQNRRGLDLLTAEQGGI | 17 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T7 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1329 | None | QNRRGLDLLFLKEGGL | 16 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T20 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1330 | Formula (IVb) CS-1 | QNRRGLDLLFWEQGGL | 16 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T21 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1331 | Formula (IVc) CS-2 | QNRLALDYLLAAEGGV | 16 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T22 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1332 | Formula (IVd) CS-3 | QARILAVERYLLDQQL | 16 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T23 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1333 | Formula (Ive)-CS-SRV 17 | QNRRGLDLLTAEQGGI | 16 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T24 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1337 | None | AQNRRGLDLLFLKEGGL | 17 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T28 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1338 | None | LQARILAVERYLKDQQL | 17 | L | None | None | None | Linear | Protein Derived | Retrovial envelope protein | Human Monocytes | Inhibit CTLL-2 proliferation | Both | Human mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T29 | NA | BALB/c and NIH/Swiss mice, Rabbits | Hummoral Immune Response assay, Monocytes O2 release assay | NA | BSA | US 4822606 | 1989 |
1359 | CDP1 | GPRGP(HP)GP(HP)GPAGL(HP)GPK | 18 | L | None | None | HP = Hydroxyproline | Linear | Protein Derived | Collagen derived | Bystander antigens | By releasing transforming growth factor β (TGF-β) | In vivo | None | NA | Rats | NA | NA | NA | US 5399347 | 1995 |
1371 | A2.94-112 | TLQRMYGCDVGSDWRFLRG | 19 | L | None | None | None | Linear | Protein Derived | α2 domain of HLA-A2 | B-Lymphoblastoid cells (B-cell) | Inhibit by binding to variable T cell receptor | In vitro | AJY CTL cell line | NA | None | Hummoral Immune Response assay | NA | NA | US 5888512 | 1999 |
1372 | A2.98-113 | MYGCDVGSDWRFLRGY | 16 | L | None | None | None | Linear | Protein Derived | α2 domain of HLA-A2 | B-Lymphoblastoid cells (B-cell) | Inhibit by binding to variable T cell receptor | In vitro | AJY CTL cell line | NA | None | Hummoral Immune Response assay | NA | NA | US 5888512 | 1999 |
1527 | Bet v 1 141-156 | GETLLRAVESYLLAHS | 16 | L | None | None | None | Linear | Protein Derived | birch pollen allergen Bet v 1 | Bet v 1-re- active Treg | Higher levels of IL-10 by Th and suppression of other T helper cells via cell-cell contact | In vitro | Mouse fibroblasts cell lines (L cells), CTLL-2 | NA | NA | CTLL-2 cell proliferation assay, ELISA, RT-PCR, FACS | NA | NA | 17202384 | 2007 |
1528 | Bet v 1 51-68 | PGTIKKISFPEGFPFKYV | 18 | L | None | None | None | Linear | Protein Derived | birch pollen allergen Bet v 2 | Bet v 1-re- active Treg | Higher levels of IL-10 by Th and suppression of other T helper cells via cell-cell contact | In vitro | Mouse fibroblasts cell lines (L cells), CTLL-3 | NA | NA | CTLL-2 cell proliferation assay, ELISA, RT-PCR, FACS | NA | NA | 17202384 | 2007 |
1529 | p33-48 | DSVTPMILKAQK GGNL | 16 | L | None | None | None | Linear | Protein Derived | Dog allergen Can f 1 | T-Cells | Elevated production of IFN-c and IL-10 | In vitro | Peptide-specific T cell lines | NA | NA | Lymphocyte proliferation assay, ELISA, FACS | NA | NA | 17233739 | 2006 |
1530 | p107-122 | RQIRMAKLLGRDPEQS | 16 | L | None | None | None | Linear | Protein Derived | Dog allergen Can f 2 | T-Cells | Elevated production of IFN-c and IL-11 | In vitro | Peptide-specific T cell lines | NA | NA | Lymphocyte proliferation assay, ELISA, FACS | NA | NA | 17233739 | 2006 |
1532 | [Y91]MBP83-99 | ENPVVHFFYNIVTPRTP | 17 | L | None | None | Mannosylation | Linear | Protein Derived | Myelin basic protein (MBP) | Th cells | Strong IFN-γ, IL-4 and IL-10 response | In vivo | NA | NA | SJL/J mice | T cell proliferation assay, ELISA, ELISpot | NA | NA | 18541301 | 2008 |
1534 | Preproinsulin-1 L7-24 peptide | FLPLLALLALWEPKPTQA | 18 | L | None | None | None | Linear | Protein Derived | Preproinsulin | IL-4, IL-10, TGF-β | Induces regulatory T cells | In vivo | NA | NA | NOD/Shi/Kbe mice | Quantikine immunoassay kit | NA | NA | 20359955 | 2010 |
1544 | HSP70 Mtb 234-252 | LREAAEKAIELSSSQSTS | 19 | L | None | None | None | Linear | Natural | M.tb. Hsp70 | Peritoneal cavity | Produce large amount of IL-10. | Both | RT1 B-restricted T cell line | NA | Male Lewis rats | ELISA | NA | NA | 10553084 | 1999 |
1547 | α3-71-91 | VNDVCNFASRNDYSYWLSTPA | 20 | L | None | None | None | Linear | Protein Derived | α3(IV)NC1 | HLA-DR15 | Produce large amount of IL-10. | in vitro | PBMC | NA | None | ELISA | NA | NA | 14569090 | 2003 |
1548 | α3-131-151 | IPPCPHGWISLWKGFSFIMF | 20 | L | None | None | None | Linear | Protein Derived | α3(IV)NC1 | HLA-DR15 | Produce large amount of IL-10. | in vitro | PBMC | NA | None | ELISA | NA | NA | 14569090 | 2003 |