Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 83
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1259SEQ ID NO:39PASKLVMGIPTFGRSF16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1260SEQ ID NO:46GTLAYYEICDFLRGAT16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1261SEQ ID NO:47EICDFLRGATVHRTLG16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1262SEQ ID NO:48RGATVHRTLGQQVPYA16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1263SEQ ID NO:53VKSKVQYLKDRQLAGA16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1264SEQ ID NO:54YLKDRQLAGAMVWALD16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1265SEQ ID NO:55LAGAMVWALDLDDFQG16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1266SEQ ID NO:56WALDLDDFQGSFCGQD16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1267SEQ ID NO:57DFQGSFCGQDLRFPLT16LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1312CKS-17LQNRRGLDLLFLKEGGL17LNoneNoneCoupled with carrier protein human serum albumin, bovine serum albuminLinearProtein DerivedHuman T-cell Leukemia Virus envelope proteinsHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T3NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1313CS-1AENRRGLDLLFWEQGGL17LNoneNoneNoneLinearProtein DerivedHuman T-cell Leukemia Virus envelope proteinsHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T4NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1314CS-2YQNRLALDYLLAAEEGV17LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T5NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1315CS-3LEARILAVERYLKDQQL17LNoneNoneNoneLinearProtein DerivedHuman T-cell Leukemia Virus envelope proteinsHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T6NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1316CS-SRV 17LQNRRGLDLLTAEQGGI17LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T7NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1329NoneQNRRGLDLLFLKEGGL16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T20NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1330Formula (IVb) CS-1QNRRGLDLLFWEQGGL16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T21NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1331Formula (IVc) CS-2QNRLALDYLLAAEGGV16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T22NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1332Formula (IVd) CS-3QARILAVERYLLDQQL16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T23NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1333Formula (Ive)-CS-SRV 17QNRRGLDLLTAEQGGI16LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T24NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1337NoneAQNRRGLDLLFLKEGGL17LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T28NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1338NoneLQARILAVERYLKDQQL17LNoneNoneNoneLinearProtein DerivedRetrovial envelope proteinHuman MonocytesInhibit CTLL-2 proliferationBothHuman mononuclear cells, Murine CTLL-2 cells, Balb/3T3 cells, NIH/3T29NABALB/c and NIH/Swiss mice, RabbitsHummoral Immune Response assay, Monocytes O2 release assayNABSAUS 48226061989
1359CDP1GPRGP(HP)GP(HP)GPAGL(HP)GPK18LNoneNoneHP = HydroxyprolineLinearProtein DerivedCollagen derivedBystander antigensBy releasing transforming growth factor β (TGF-β)In vivoNoneNARatsNANANAUS 53993471995
1371A2.94-112TLQRMYGCDVGSDWRFLRG19LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroAJY CTL cell lineNANoneHummoral Immune Response assayNANAUS 58885121999
1372A2.98-113MYGCDVGSDWRFLRGY16LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroAJY CTL cell lineNANoneHummoral Immune Response assayNANAUS 58885121999
1527Bet v 1 141-156GETLLRAVESYLLAHS16LNoneNoneNoneLinearProtein Derivedbirch pollen allergen Bet v 1Bet v 1-re- active TregHigher levels of IL-10 by Th and suppression of other T helper cells via cell-cell contactIn vitroMouse fibroblasts cell lines (L cells), CTLL-2NANACTLL-2 cell proliferation assay, ELISA, RT-PCR, FACSNANA172023842007
1528Bet v 1 51-68PGTIKKISFPEGFPFKYV18LNoneNoneNoneLinearProtein Derivedbirch pollen allergen Bet v 2Bet v 1-re- active TregHigher levels of IL-10 by Th and suppression of other T helper cells via cell-cell contactIn vitroMouse fibroblasts cell lines (L cells), CTLL-3NANACTLL-2 cell proliferation assay, ELISA, RT-PCR, FACSNANA172023842007
1529p33-48DSVTPMILKAQK GGNL16LNoneNoneNoneLinearProtein DerivedDog allergen Can f 1T-CellsElevated production of IFN-c and IL-10In vitroPeptide-specific T cell linesNANALymphocyte proliferation assay, ELISA, FACSNANA172337392006
1530p107-122RQIRMAKLLGRDPEQS16LNoneNoneNoneLinearProtein DerivedDog allergen Can f 2T-CellsElevated production of IFN-c and IL-11In vitroPeptide-specific T cell linesNANALymphocyte proliferation assay, ELISA, FACSNANA172337392006
1532[Y91]MBP83-99ENPVVHFFYNIVTPRTP17LNoneNoneMannosylationLinearProtein DerivedMyelin basic protein (MBP)Th cellsStrong IFN-γ, IL-4 and IL-10 responseIn vivoNANASJL/J miceT cell proliferation assay, ELISA, ELISpotNANA185413012008
1534Preproinsulin-1 L7-24 peptideFLPLLALLALWEPKPTQA18LNoneNoneNoneLinearProtein DerivedPreproinsulinIL-4, IL-10, TGF-βInduces regulatory T cellsIn vivoNANANOD/Shi/Kbe miceQuantikine immunoassay kitNANA203599552010
1544HSP70 Mtb 234-252LREAAEKAIELSSSQSTS19LNoneNoneNoneLinearNaturalM.tb. Hsp70Peritoneal cavityProduce large amount of IL-10.BothRT1 B-restricted T cell lineNAMale Lewis ratsELISANANA105530841999
1547α3-71-91VNDVCNFASRNDYSYWLSTPA20LNoneNoneNoneLinearProtein Derivedα3(IV)NC1HLA-DR15Produce large amount of IL-10.in vitroPBMCNANoneELISANANA145690902003
1548α3-131-151IPPCPHGWISLWKGFSFIMF20LNoneNoneNoneLinearProtein Derivedα3(IV)NC1HLA-DR15Produce large amount of IL-10.in vitroPBMCNANoneELISANANA145690902003