Detailed description page of ImmunoSPdb

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1527 details
Primary information
ID1527
Peptide NameBet v 1 141-156
SequenceGETLLRAVESYLLAHS
Length16
ChiralityL
N-terminal ModificationNone
C-terminal ModificationNone
Chemical ModificationNone
Linear/ CyclicLinear
NatureProtein Derived
Source of Originbirch pollen allergen Bet v 1
TargetBet v 1-re- active Treg
Mechanism of ActionHigher levels of IL-10 by Th and suppression of other T helper cells via cell-cell contact
In vitro/In vivoIn vitro
Cell LineMouse fibroblasts cell lines (L cells), CTLL-2
Inhibition ConcentartionNA
In vivo ModelNA
AssayCTLL-2 cell proliferation assay, ELISA, RT-PCR, FACS
Lethal DoseNA
Combination TherapyNA
Pubmed ID17202384
Year of Publication2007
3-D Structure View in Jmol or Download Structure