| Primary information |
|---|
| ID | 1088 |
| Peptide Name | ISU-peptide |
| Sequence | LQARILAVERYLKDQQL |
| Length | 17 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Protein Derived |
| Source of Origin | HIV-1 isolate HXB2 |
| Target | IL-2 |
| Mechanism of Action | HIV env 583-599 conjugated to a carrier protein to inhibit the cytopathic effect of HIV-1. This inhibition of vims replication may be due to blocking of a secondary receptor, to inhibition of target cell proliferation preventing virus replication or to both effects |
| In vitro/In vivo | Both |
| Cell Line | Murine CTL-6, human T-cell lines MT4, Molt4/clone 8 |
| Inhibition Concentartion | NA |
| In vivo Model | Balb/c mice |
| Assay | Lymphocyte Proliferation assays, cytopathogenicity assay |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | 7986401 |
| Year of Publication | 1994 |
| 3-D Structure |  View in Jmol or Download Structure |
