Browse result page of AntiTbPdb
The total number entries retrieved from this search are 110
| ID | Name | Sequence | N-Terminal Modification | C-Terminal Modification | Chemical Modification | Linear/Cyclic | Length | Chirality | Nature | Source | Origin | Species | Strain | Inhibition Concentration | In vitro/ In vivo | Cell Line | Intracellular Inhibition | Cytotoxicity | Animal Model | Effective Dose in model organism | Immune Responce | Mechanism of Action | Target | Combination Therapy | Other Activities | Year of Publication | Pubmed ID/ Patent No. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| antitb_1780 | Peptide-24 | GF-Tic-Oic-GK-Tic-Oic-GF-Tic-Oic-GK-Tic-KKKK | Acetylation | Addition of -CONH-CH2-CH2-NH2 | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 25 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1781 | Peptide-25 | GF-Tic-Oic-GK-Tic-Oic-GF-Tic-Oic-GK-Tic-KKKK | Acetylation | Addition of CONH-CH2-CH2-CH2-NH2 | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 25 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1784 | Peptide-28 | F-Tic-Oic-K-Tic-Oic-F-Tic-Oic-K-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 15 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 30 µM or 66 µg/mL | Both | RBC | NA | 86.8 % and 50 % hemolytic activity at 100 µM and 25 µM peptide respectively | mouse skin wound healing model | No toxicity observed at 25 mg/kg for 6 days | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1785 | Peptide-29 | GABA-F-Tic-Oic-GABA-K-Tic-Oic-GABA-F-Tic-Oic-GABA-K-Tic-KKKK | Acetylation | Amidation | GABA = Gama aminobutyric acid, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 28 µg/mL | Both | RBC | NA | 10.8 % and 1 % hemolytic activity at 100 µM and 25 µM peptide respectively | mouse skin wound healing model | No toxicity observed at 25 mg/kg for 6 days | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1786 | Peptide-30 | G-Tic-Oic-K-Tic-Oic-G-Tic-Oic-K-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 15 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 3 µM or 6 µg/mL | Both | RBC | NA | 26.7 % and 9.2 % hemolytic activity at 100 µM and 25 µM peptide respectively | mouse skin wound healing model | No toxicity observed at 25 mg/kg for 6 days | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1787 | Peptide-31 | GF-Oic-GK-Oic-GF-Oic-GKKKKK | Acetylation | Amidation | Oic = Octahydroindolecarboxylic acid | Linear | 15 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 100 µM or 180 µg/mL | Both | RBC | NA | 5.9 % and 3.2 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1788 | Peptide-32 | GF-Tic-GK-Tic-GF-Tic-GK-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid | Linear | 15 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 30 µM or 60 µg/mL | Both | RBC | NA | 6 % and 4.9 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1789 | Peptide-33 | GF-Tic-G-GK-Tic-G-GF-Tic-G-GK-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 30 µM or 66 µg/mL | Both | RBC | NA | 5.70 % and 3.80 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1790 | Peptide-34 | GF-G-Oic-GK-G-Oic-GF-G-Oic-GK-G-KKKK | Acetylation | Amidation | Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 100 µM or 200 µg/mL | Both | RBC | NA | 3.3 % and 3.30 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1791 | Peptide-35 | GF-F-Oic-GK-F-Oic-GF-F-Oic-GK-F-KKKK | Acetylation | Amidation | Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 24 µg/mL | Both | RBC | NA | 27.30 % and 8.9 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1792 | Peptide-36 | βAla-F-Tic-Oic-βAla-K-Tic-Oic-βAla-F-Tic-Oic-βAla-K-Tic-KKKK | Acetylation | Amidation | βAla= beta-alanine, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 1 µM or 2.5 µg/mL | Both | RBC | NA | 24.4 % and 7.4 % hemolytic activity at 100 µM and 25 µM peptide respectively | mouse skin wound healing model | Acute toxicity was observed at dose of 125 mg/kg | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1793 | Peptide-37 | Ahx-F-Tic-Oic-Ahx-K-Tic-Oic-Ahx-F-Tic-Oic-Ahx-K-Tic-KKKK | Acetylation | Amidation | Ahx = 6-amino hexanoic acid, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 3 µM or 8.1 µg/mL | Both | RBC | NA | 44.7 % and 26.6 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1794 | Peptide-38 | F-Tic-Oic-K-Tic-Oic-F-Tic-Oic-K-Tic-KKKKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 17 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 3 µM or 7.5 µg/mL | Both | RBC | NA | 41.3 % and 33.5 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1795 | Peptide-39 | GF-Tic-Oic-GK-Tic-Oic-GF-Tic-Oic-GK-Tic-KKKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 3 µM or 7.8 µg/mL | Both | RBC | NA | 24.9 % and 18.9 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1796 | Peptide-40 | GABA-F-Tic-Oic-GABA-K-Tic-Oic-GABA-F-Tic-Oic-GABA-K-Tic-KKKKK | Acetylation | Amidation | GABA = Gama aminobutyric acid, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 3 µM or 8.1 µg/mL | Both | RBC | NA | 29.7 % and 10.5 % hemolytic activity at 100 µM and 25 µM peptide respectively | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1797 | Peptide-41 | GF-Tic-Oic-GK-Tic-Oic-GF-Tic-Oic-GK-Tic-Orn-Orn-Orn-Orn | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid, Orn = Ornithine | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 24 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1798 | Peptide-42 | G-Fpa-Tic-Oic-GK-Tic-Oic-G-Fpa-Tic-Oic-GK-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid, Fpa = 4-fluorophenylalanine | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 3 µM or 7.5 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1799 | Peptide-43 | GF-Tic-Oic-G-Orn-Tic-Oic-GF-Tic-Oic-G-Orn-Tic-Orn-Orn-Orn-Orn | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid, Orn = Ornithine | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 24 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1801 | Peptide-45 | GF-Tic-Oic-G-Dpr-Tic-Oic-GF-Tic-Oic-G-Dpr-Tic-Dpr-Dpr-Dpr-Dpr | Acetylation | Amidation | Dpr = diaminopropionic acid, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 100 µM or 220 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1802 | Peptide-46 | βAla-Fpa-Tic-Oic-βAla-Dpr-Tic-Oic-βAla-Fpa-Tic-Oic-βAla-Dpr-Tic-Dpr-Dpr-Dpr-Dpr | Acetylation | Amidation | βAla = beta-alanine, Fpa, 4-fluorophenylalanine, Dpr = diaminopropionic acid, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 100 µM or 228 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1803 | Peptide-47 | G-f-Tic-Oic-GK-Tic-Oic-G-f-Tic-Oic-GK-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | Mix | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 24 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1804 | Peptide-48 | GF-Tic-Oic-G-k-Tic-Oic-GF-Tic-Oic-G-k-Tic-KKKK | Acetylation | Amidation | Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | Mix | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 24 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1805 | Peptide-49 | G-Nph-Tic-Oic-GK-Tic-Oic-G-Nph-Tic-Oic-GK-Tic-KKKK | Acetylation | Amidation | Nph = 4-nitrophenylalanine, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 19 | L | Amphipathic, Hydrophobic | Synthetic | NA | Mycobacterium ranae | Mycobacterium ranae (ATCC 110) | MIC = 10 µM or 25 µg/mL | Both | NA | NA | Not tested | NA | NA | Stimulate innate immune system | NA | NA | NA | Antibacterial (Salmonella typhimurium (ATCC 13311), Staphylococcus aureus methicillin/gentamicin/tetrac+AB20ycline resistant (ATCC 33592), Bacillus subtillis (ATCC 43223)) | 2007 | 17547385 |
| antitb_1916 | Peptide-1 | GF(A6c)G(A6c)KK(A6c)G(A6c)F(A6c)G(A6c)GKK(A6c)KKKK | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 22 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC =4.92 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1917 | Peptide-2 | GF(A6c)G(A6c)R(A6c)G(A6c)F(A6c)G(A6c)GR(A6c)RRRR | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 19 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 40.75 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1918 | Peptide-3 | GF(A6c)G(A6c)Orn(A6c)G(A6c)F(A6c)G(A6c)GOrn(A6c)Orn-Orn- Orn- Orn | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, orn = ornithine | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 11.37 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1919 | Peptide-4 | GF(A6c)G(A6c)Dab(A6c)G(A6c)F(A6c)G(A6c)GDab(A6c)Dab-Dab-Dab-Dab | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Dab = 2,4-diaminobutyric acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC =11.83 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1920 | Peptide-5 | GF(A6c)G(A6c)Dpr(A6c)G(A6c)F(A6c)G(A6c)GDpr(A6c) Dpr-Dpr-Dpr- Dpr | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Dpr = 2,4-diaminopropanoic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 24.63 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1921 | Peptide-6 | GF(A5c)G(A5c)K(A5c)G(A5c)F(A5c)G(A5c)GK(A5c)KKKK | Acetylation | Amidation | A5c = 1-aminocyclopentane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 11.42 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1922 | Peptide-7 | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR | Acetylation | Amidation | A5c = 1-aminocyclopentane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC =21.22 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1923 | Peptide-8 | GF(A6c)G(Tic)K(A6c)G(Tic)F(A6c)G(Tic)GK(Tic)KKKK | Acetylation | Amidation | Tic = Tetrahydroisoquinolinecarboxylic acid, A6c 1-aminocyclohexane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 10.33 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1924 | Peptide-9 | GF(A6c)G(Oic)K(A6c)G(Oic)F(A6c)G(Oic)GK(Oic)KKKK | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 20.92 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1925 | Peptide-10 | GF(A5c)G(A6c)K(A5c)G(A6c)F(A5c)G(A6c)GK(A5c)KKKK | Acetylation | Amidation | A5c = 1-aminocyclopentane carboxylic acid, A6c 1-aminocyclohexane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 22.42 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1926 | Peptide-11 | KKKKGF(A6c)G(A6c)K(A6c)G(A6c)F(A6c)G(A6c)GK(A6c) | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = 21.87 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1927 | Peptide-1 | GF(A6c)G(A6c)KK(A6c)G(A6c)F(A6c)G(A6c)GKK(A6c)KKKK | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 22 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC =4.92 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1928 | Peptide-2 | GF(A6c)G(A6c)R(A6c)G(A6c)F(A6c)G(A6c)GR(A6c)RRRR | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 19 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 40.75 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1929 | Peptide-3 | GF(A6c)G(A6c)Orn(A6c)G(A6c)F(A6c)G(A6c)GOrn(A6c)Orn-Orn- Orn- Orn | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, orn = ornithine | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 11.37 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1930 | Peptide-4 | GF(A6c)G(A6c)Dab(A6c)G(A6c)F(A6c)G(A6c)GDab(A6c)Dab-Dab-Dab-Dab | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Dab = 2,4-diaminobutyric acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC =25.65 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1931 | Peptide-5 | GF(A6c)G(A6c)Dpr(A6c)G(A6c)F(A6c)G(A6c)GDpr(A6c) Dpr-Dpr-Dpr- Dpr | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Dpr = 2,4-diaminopropanoic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 49.26 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1932 | Peptide-6 | GF(A5c)G(A5c)K(A5c)G(A5c)F(A5c)G(A5c)GK(A5c)KKKK | Acetylation | Amidation | A5c = 1-aminocyclopentane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 22.85 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1933 | Peptide-7 | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR | Acetylation | Amidation | A5c = 1-aminocyclopentane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC >43 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1934 | Peptide-8 | GF(A6c)G(Tic)K(A6c)G(Tic)F(A6c)G(Tic)GK(Tic)KKKK | Acetylation | Amidation | Tic = Tetrahydroisoquinolinecarboxylic acid, A6c 1-aminocyclohexane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 20.6μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1935 | Peptide-9 | GF(A6c)G(Oic)K(A6c)G(Oic)F(A6c)G(Oic)GK(Oic)KKKK | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Oic = Octahydroindolecarboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 20.92 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1936 | Peptide-10 | GF(A5c)G(A6c)K(A5c)G(A6c)F(A5c)G(A6c)GK(A5c)KKKK | Acetylation | Amidation | A5c = 1-aminocyclopentane carboxylic acid, A6c 1-aminocyclohexane carboxylic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 11.21 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1937 | Peptide-11 | KKKKGF(A6c)G(A6c)K(A6c)G(A6c)F(A6c)G(A6c)GK(A6c) | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis MDR | MIC = 5.47 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1938 | Peptide-1 | GF(A6c)G(A6c)KK(A6c)G(A6c)F(A6c)G(A6c)GKK(A6c)KKKK | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 22 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis XDR | MIC =4.92 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1939 | Peptide-2 | GF(A6c)G(A6c)R(A6c)G(A6c)F(A6c)G(A6c)GR(A6c)RRRR | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, | Linear | 19 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis XDR | MIC = 10.19 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1940 | Peptide-3 | GF(A6c)G(A6c)Orn(A6c)G(A6c)F(A6c)G(A6c)GOrn(A6c)Orn-Orn- Orn- Orn | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, orn = ornithine | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis XDR | MIC = 11.37 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1941 | Peptide-4 | GF(A6c)G(A6c)Dab(A6c)G(A6c)F(A6c)G(A6c)GDab(A6c)Dab-Dab-Dab-Dab | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Dab = 2,4-diaminobutyric acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis XDR | MIC =25.65 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |
| antitb_1942 | Peptide-5 | GF(A6c)G(A6c)Dpr(A6c)G(A6c)F(A6c)G(A6c)GDpr(A6c) Dpr-Dpr-Dpr- Dpr | Acetylation | Amidation | A6c = 1-aminocyclohexane carboxylic acid, Dpr = 2,4-diaminopropanoic acid | Linear | 20 | D | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis XDR | MIC = 49.26 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | Cell wall pore formation | NA | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus | 2016 | 27387357 |