| Primary information |
|---|
| ID | antitb_1922, |
| Name | 27387357 |
| N-Terminal modification | Peptide-7 |
| C-Terminal Modification | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR |
| Chemical Modification | Acetylation |
| Linear/Cyclic | Amidation |
| Length | A5c = 1-aminocyclopentane carboxylic acid |
| Chirality | Linear |
| Nature | 20 |
| Source | D |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
| Cell Line | MIC =21.22 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2016 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | Cell wall pore formation |
| PMID | NA |
| Year of Publication | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus |
Tertiary Structure
(Technique) | Not Predicted), |
| Primary information |
|---|
| ID | antitb_1933, |
| Name | 27387357 |
| N-Terminal modification | Peptide-7 |
| C-Terminal Modification | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR |
| Chemical Modification | Acetylation |
| Linear/Cyclic | Amidation |
| Length | A5c = 1-aminocyclopentane carboxylic acid |
| Chirality | Linear |
| Nature | 20 |
| Source | D |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis MDR |
| Cell Line | MIC >43 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2016 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | Cell wall pore formation |
| PMID | NA |
| Year of Publication | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus |
Tertiary Structure
(Technique) | Not Predicted), |
| Primary information |
|---|
| ID | antitb_1944, |
| Name | 27387357 |
| N-Terminal modification | Peptide-7 |
| C-Terminal Modification | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR |
| Chemical Modification | Acetylation |
| Linear/Cyclic | Amidation |
| Length | A5c = 1-aminocyclopentane carboxylic acid |
| Chirality | Linear |
| Nature | 20 |
| Source | D |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium tuberculosis |
| In Vitro/ In vivo | Mycobacterium tuberculosis XDR |
| Cell Line | MIC >43 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2016 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | Cell wall pore formation |
| PMID | NA |
| Year of Publication | Antibacterial against Enterobacter aerogenes, Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae, Eenterococcus faecalis, Staphylococcus aureus |
Tertiary Structure
(Technique) | Not Predicted), |